Prevention of Blood Specimen Hemolysis in Peripherally-Collected Venous Specimens
Publication Date: July 1, 2018
Last Updated: March 14, 2022
Decision Options
Before the Draw Preparation and Equipment Selection
Education of the staff performing phlebotomy may decrease hemolysis. (B)
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Low (partial) vacuum tubes result in less hemolysis. (B)
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Direct venipuncture with straight needles is less likely to cause hemolysis than blood collection through intravenous catheters. (B)
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The type of personnel performing phlebotomy does not influence hemolysis. (C)
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Stainless steel needles are less likely to cause hemolysis than intravenous catheters; Teflon catheters are less likely to cause hemolysis than Vialon™ catheters. (C)
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There is conflicting evidence regarding the influence of needle or catheter gauge on hemolysis. (I/E)
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There is conflicting evidence regarding hemolysis with syringes vs. vacuum tubes. (I/E)
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Title
Prevention of Blood Specimen Hemolysis in Peripherally-Collected Venous Specimens
Authoring Organization
Emergency Nurses Association