Early Pregnancy Loss

Publication Date: October 31, 2018
Last Updated: March 14, 2022

Recommendations

In patients for whom medical management of early pregnancy loss is indicated, initial treatment using 800 micrograms of vaginal misoprostol is recommended, with a repeat dose as needed. The addition of a dose of mifepristone (200 mg orally) 24 hours before misoprostol administration may significantly improve treatment efficacy and should be considered when mifepristone is available. (A)
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Overview

Title

Early Pregnancy Loss

Authoring Organization

American College of Obstetricians and Gynecologists