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Neural tube defects
Publication Date: December 1, 2017
Last Updated: March 14, 2022
Summary of Recommendations
The following recommendations are based on good and consistent scientific evidence.
All women planning a pregnancy or capable of becoming pregnant should take 400 micrograms of folic acid supplementation daily. Supplementation should begin at least 1 month before pregnancy and continue through the first 12 weeks of pregnancy.
Women at high risk of NTDs should take 4 mg (4,000 micrograms) of folic acid daily. The daily supplement should be initiated 3 months before pregnancy and continued until 12 weeks of gestational age.
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Overview
Title
Neural Tube Defects
Authoring Organization
American College of Obstetricians and Gynecologists
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