Treatment of Metastatic Carcinoma and Myeloma of the Femur

Publication Date: October 1, 2020

Overview

Overview

  • The skeleton is a frequent site of metastasis in patients with cancer.
  • Multiple myeloma is a plasma cell malignancy in which 70-80% of patients present with lytic lesions in the skeleton.
  • Bone lesions, whether from metastatic carcinoma or multiple myeloma, can be painful and limit physical activity.
    • They may require radiation therapy, surgery or both.
  • Metastatic carcinoma or myeloma bone lesions that progress to pathologic fracture diminish functional capacity and quality of life and can potentially reduce overall survival.

Management

...nagemen...

...ng and Clinical Findings...

...e of reliable evidence, it is the opinion of...


...y of Bone Modifying Agents (BMAs)...

...ce of reliable evidence, it is the op...


Dosage Response...

...ians should consider decreasing the freque...


...MAs for Various Dia...

...e of reliable evidence, it is the opinion o...


...ng Findings and Atypical Fractu...

...of reliable evidence, it is the opinion...


...of Radiation Therapy...

...hould consider the use of radiation therapy to d...


...rapy and Prophylactic Femur Stabilization...

...bsence of reliable evidence, it is the opinio...


...Therapy after Resection and Recons...

...sence of reliable evidence, it is the opini...


...ulti-Fraction Radiation Trea...

...hould consider the use of multi-fr...


...vival and Reconstruction Method...

...he absence of reliable evidence, it is th...


...tem Hemiarthroplast...

...e absence of reliable evidence, it is the opi...


Cephalomedullary Na...

...nce of reliable evidence, it is the opinion...


...throplasty...

...ans may consider arthroplasty to improve patien...