Treatment of Metastatic Carcinoma and Myeloma of the Femur

Publication Date: October 1, 2020

Overview

Overview

  • The skeleton is a frequent site of metastasis in patients with cancer.
  • Multiple myeloma is a plasma cell malignancy in which 70-80% of patients present with lytic lesions in the skeleton.
  • Bone lesions, whether from metastatic carcinoma or multiple myeloma, can be painful and limit physical activity.
    • They may require radiation therapy, surgery or both.
  • Metastatic carcinoma or myeloma bone lesions that progress to pathologic fracture diminish functional capacity and quality of life and can potentially reduce overall survival.

Management

...Management...

...Imaging and Clinic...

...e of reliable evidence, it is the opinion...


...Efficac...

...absence of reliable evidence, it is the opi...


...Dosage Respons...

...ns should consider decreasing the frequency...


...BMAs...

...absence of reliable evidence, it is...


...Imaging Findings...

...ce of reliable evidence, it is the opinion of t...


...Effica...

...ians should consider the use of radi...


...Radiation Therapy and...

...he absence of reliable evidence, it is the opin...


...Radiation Therapy after...

...of reliable evidence, it is the opinion of...


...Multi-Fract...

...linicians should consider the use...


...Estimating Surviv...

...he absence of reliable evidence, it is t...


...the absence of reliable evidence, it is th...


...Cephalomedullary Nailing...

...of reliable evidence, it is the opinion of the...


...Arthropl...

...y consider arthroplasty to improve patient functi...