Management of Adrenal Incidentalomas

Publication Date: June 15, 2023
Last Updated: August 2, 2023

General remarks


We recommend that patients with adrenal incidentalomas are discussed in a multidisciplinary expert team meeting, if at least one of the following criteria is met:
  • Imaging is not consistent with a benign lesion.
  • There is evidence of hormone excess (including mild autonomous cortisol secretion [MACS] in patients with clinically relevant comorbidities potentially attributable to cortisol).
  • Adrenal surgery is considered.
  • Evidence of significant tumor growth during follow-up imaging.
The core multidisciplinary team should consist of a radiologist, an endocrinologist, and a surgeon, all with significant experience in the management of adrenal tumors. (, )

Assessment of the risk of malignancy


We recommend aiming to establish with the highest possible certainty if an adrenal mass is benign or malignant at the time of initial detection. (, )



Management of Adrenal Incidentalomas

Authoring Organization