ASH/ISTH/NBDF/WFH Management of Von Willebrand Disease Guideline Summary - Guideline Central

Document Overview

Design and created by Guideline Central in participation with the American Society of Hematology, International Society on Thrombosis and Haemostasis, National Bleeding Disorders Foundation, and World Federation of Hemophilia.

Document Overview

Document Title: Management of Von Willebrand Disease

Authoring Societies

American Society of Hematology

National Bleeding Disorders Foundation

International Society on Thrombosis and Haemostasis

World Federation of Hemophilia

Document Publication Date: Jan 12, 2021

Page Last Reviewed/Updated: May 6, 2026

Document Type: Guideline

Country of Publication: United States

Full Text Freely Available: Yes

Full Text Guideline: doi.org/10.1182/bloodadvances.2020003264

Supplemental Implementation Resources

Document Scope, Criteria, and Use Cases

Scope: Assessment and Screening, Management, Treatment

Diseases/Conditions (MeSH)

D014842 - von Willebrand Diseases

D014842 - von Willebrand Diseases

Keywords: prophylaxis, thrombosis and hemostasis, von Willebrand

Inclusion Criteria: Female, Adolescent, Adult

Health Care Settings: Ambulatory, Emergency Care, Hospital

Intended Users: Nurse, Nurse Practitioner, Physician, Physician Assistant, Social Worker

Recommendation Development Processes & Methodology

Number of Source Documents: 130

Includes peer/external review process?: Yes

Includes public comment process?: No

Methodologist involvement?: Yes

Patient involvement?: No

Includes multi-disciplinary group?: Yes

Includes systematic review?: Yes

Grades quality of strength of evidence?: Yes

Grades quality of strength of recommendation?: Yes

Discloses funding source?: Yes

Discloses conflicts of interest?: Yes

Includes benefits/harms analysis with recommendations?: Yes