Acute Treatment of Cerebral Edema in Neurocritical Care Patients

Publication Date: May 31, 2020
Last Updated: March 14, 2022

Recommendations

Treatment of Cerebral Edema in Patients with Subarachnoid Hemorrhage

1. We suggest using symptom-based bolus dosing of hypertonic sodium solutions rather than sodium target-based dosing for the management of ICP or cerebral edema in patients with SAH (conditional recommendation, very low-quality evidence)
Rationale: In making this recommendation, the panel felt that while the quality of evidence was very low, the consistency of the literature justifed symptom-based bolus dosing of HTS as an efective means of reducing ICP and cerebral edema in patients with SAH. Te data on sodium target-based HTS dosing regimens for ICP control were extremely limited and provided only indirect evidence and thus could not be recommended.
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2. Due to insufficient evidence, we cannot recommend a specifc dosing strategy for HTS to improve neurological outcomes in patients with SAH.
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Overview

Title

Acute Treatment of Cerebral Edema in Neurocritical Care Patients

Authoring Organization

Neurocritical Care Society