Title

Management of Moderate to Severe Ulcerative Colitis

Authoring Organization

American Gastroenterological Association

Publication Month/Year

January 13, 2020

Last Updated Month/Year

October 3, 2024

Document Type

Guideline

External Publication Status

Published

Country of Publication

US

Document Objectives

This document presents the official recommendations of the American Gastroenterological Association (AGA) on the management of moderate to severe ulcerative colitis (UC). This guideline addresses the medical management of adult outpatients with moderate to severe UC, as well as the medical management of adult hospitalized patients with ASUC. The guideline focuses on immunomodulators, biologics, and small molecules for induction and maintenance of remission (for moderate to severe UC) and decreasing the risk of colectomy (for ASUC).

Target Patient Population

Adult outpatients with moderate to severe ulcerative colitis (UC) and adult hospitalized patients with acute severe ulcerative colitis (ASUC)

Inclusion Criteria

Male, Female, Adult

Health Care Settings

Ambulatory, Hospital, Outpatient

Intended Users

Nurse, nurse practitioner, physician, physician assistant

Scope

Treatment, Management

Keywords

inflammatory bowel disease, ulcerative colitis, ulcer

Source Citation

Feuerstein JD, Isaacs KL, Schneider Y, Siddique SM, Falck-Ytter Y, Singh S, on behalf of the American Gastroenterological Association Institute Clinical Guidelines Committee, AGA Clinical Practice Guidelines on the Management of Moderate to Severe Ulcerative Colitis, Gastroenterology (2020), doi: https://doi.org/10.1053/j.gastro.2020.01.006.

Supplemental Methodology Resources

Technical Review