Lung Cancer Surveillance After Definitive Curative-Intent Therapy
Key Points
Key Points
Non-Small Cell Lung Cancer
The chance of NSCLC recurrence is greatest during the first 2 years following treatment with curative intent.
- Patients with an intrathoracic recurrence may be salvaged with surgical resection, stereotactic body radiotherapy (SBRT) or chemoradiation depending on the clinical scenario.
- Early identification of extra-thoracic metastatic recurrence may allow prompt molecular testing and facilitate the safe administration of precision palliative therapy before patients develop severe symptoms or deteriorate.
Two or more years after curative intent therapy, patients are at higher risk of developing a second primary lung cancer (1.5-2% per year) and may benefit from screening.
Small Cell Lung Cancer
- The risk of intracranial recurrence is significant. Therefore, close central nervous system (CNS) surveillance may afford treatment before permanent neurologic sequelae develop from symptomatic SCLC brain metastases.
Recommendations
Recommendat...
...recommendations apply to patients w...
...undergo surveillance imaging for recur...
...s should undergo surveillance imagi...
...inicians should use a diagnostic chest CT tha...
...ians should use a low dose screening c...
...nicians should NOT use FDG-PET/CT as a survei...
...aging may be omitted in patients who are...
...ld NOT use circulating biomarkers as a surveilla...
...tage I-III NSCLC patients, clinicians shoul...
...have undergone curative intent treatment...