Management of Acute Coronary Syndromes

Authoring Organization

Publication Month/Year

August 25, 2023

Supplemental Implementation Tools

Document Type


Country of Publication


Document Objectives

The present guideline has been developed to support healthcare professionals in the diagnosis and management of patients presenting with acute coronary syndrome (ACS). The conditions of ST-elevation myocardial infarction (STEMI) and non-ST-elevation ACS (NSTE-ACS) have been covered separately in previous European Guidelines. For the first time, the present guideline presents recommendations for management of patients across the entire spectrum of ACS in one document. The previous guidelines on STEMI were published in 2017 and the previous guidelines on NSTE-ACS were published in 2020. There have been numerous developments in the diagnosis and treatment of patients with ACS in the intervening years, which are reflected in this up-to-date guideline. The current guideline provides a comprehensive overview of the management of patients presenting with ACS, from the point of diagnosis and risk stratification at initial presentation, through to long term management after the initial hospitalisation period. Particular focus is given to the importance of anti-thrombotic therapy, invasive assessment and revascularisation. This guideline also highlights the importance of providing patient centered care throughout the patients ACS journey

Inclusion Criteria

Male, Female, Adult, Older adult

Health Care Settings

Ambulatory, Hospital, Outpatient

Intended Users

Nurse, nurse practitioner, physician, physician assistant



Diseases/Conditions (MeSH)

D054058 - Acute Coronary Syndrome


acute coronary syndrome, acute coronary syndromes, ACS

Source Citation

Robert A Byrne and others, 2023 ESC Guidelines for the management of acute coronary syndromes: Developed by the task force on the management of acute coronary syndromes of the European Society of Cardiology (ESC), European Heart Journal, 2023;, ehad191, https://doi.org/10.1093/eurheartj/ehad191