Microbiological Laboratory Testing in the Diagnosis of Fungal Infections in Pulmonary and Critical Care Practice
Key Points
Key Points
- The rising prevalence of fungal infections is likely related to several factors, including an ever-growing population of susceptible patients.
- Furthermore, endemic mycoses continue to pose a threat to both immunocompetent and immunosuppressed individuals.
- Recent advances in laboratory diagnostics have evolved to assist the diagnosis of pulmonary fungal infections.
- These guidelines focus on the use of galactomannan (GM) antigen and PCR testing in the diagnosis of invasive pulmonary aspergillosis (IPA), (1➝3)-β-D-glucan (BDG) assays or invasive candidiasis (IC), and the use of antigen and antibody testing in the diagnosis of endemic mycoses.
Diagnosis
Diagno...
.... Recommendations...
...vasive fungal disease...
...severe immune compromise, such as those...
...uspected of invasive fungal diseases, including t...
...nvasive pulmonary aspe...
...nts with severe immune compromise, such as those...
...ients with severe immune compromis...
...n patients with severe immune compromise, s...
...didiasis...
...l patients in whom there is clinical co...
...istoplasmosis
...recommends the use of Histoplasma...
...sts the use of Histoplasma serologies in im...
...tomycosis...
...ients with appropriate geographic exposure an...
...patients with suspected blastomycosi...
...with suspected blastomycosis, parti...
...cidioidomycosi...
...n patients with appropriate geographic exposure a...
...h suspected coccidioidomycosis, parti...
...tients with suspected community acquired pneumo...