Microbiological Laboratory Testing in the Diagnosis of Fungal Infections in Pulmonary and Critical Care Practice

Publication Date: September 1, 2019

Key Points

Key Points

  • The rising prevalence of fungal infections is likely related to several factors, including an ever-growing population of susceptible patients.
  • Furthermore, endemic mycoses continue to pose a threat to both immunocompetent and immunosuppressed individuals.
  • Recent advances in laboratory diagnostics have evolved to assist the diagnosis of pulmonary fungal infections.
  • These guidelines focus on the use of galactomannan (GM) antigen and PCR testing in the diagnosis of invasive pulmonary aspergillosis (IPA), (1➝3)-β-D-glucan (BDG) assays or invasive candidiasis (IC), and the use of antigen and antibody testing in the diagnosis of endemic mycoses.

Diagnosis

...agnosis...

Table 2. Recommendati...

...e fungal disease...

...patients with severe immune compromise, such as...

...uspected of invasive fungal diseases,...

...sive pulmonary aspergill...

...h severe immune compromise, such as...

In patients with severe immune compromi...

...atients with severe immune compromise, such...

...ndidiasis...

...l patients in whom there is clinical con...

...istoplasmosi...

...recommends the use of Histoplasma antigen...

...s the use of Histoplasma serologies in immunocompe...

...stomycosis...

...nts with appropriate geographic exposu...

...s with suspected blastomycosis, the...

...patients with suspected blastomycosis, particu...

...ccidioidomyco...

...nts with appropriate geographic exposure and i...

...with suspected coccidioidomycosis, particula...

...with suspected community acquired pneumon...