Microbiological Laboratory Testing in the Diagnosis of Fungal Infections in Pulmonary and Critical Care Practice

Publication Date: September 1, 2019

Key Points

Key Points

  • The rising prevalence of fungal infections is likely related to several factors, including an ever-growing population of susceptible patients.
  • Furthermore, endemic mycoses continue to pose a threat to both immunocompetent and immunosuppressed individuals.
  • Recent advances in laboratory diagnostics have evolved to assist the diagnosis of pulmonary fungal infections.
  • These guidelines focus on the use of galactomannan (GM) antigen and PCR testing in the diagnosis of invasive pulmonary aspergillosis (IPA), (1➝3)-β-D-glucan (BDG) assays or invasive candidiasis (IC), and the use of antigen and antibody testing in the diagnosis of endemic mycoses.

Diagnosis

...iagnos...

...ble 2. Recommendations...

...ive fungal disease...

...patients with severe immune compro...

...nts suspected of invasive fungal diseas...

Invasive pulmonary aspergillos...

...with severe immune compromise, such as tho...

...patients with severe immune compromise, su...

...ents with severe immune compromise, such as those...

...didiasis...

...y ill patients in whom there is clinical con...

...toplasmosis

...TS recommends the use of Histoplasma a...

...TS suggests the use of Histoplasma se...

...lastomycosi...

...tients with appropriate geographic expo...

...with suspected blastomycosis, the ATS sugg...

...h suspected blastomycosis, particu...

...cidioidomycosis...

...patients with appropriate geographic exposure and...

...th suspected coccidioidomycosis, particularly...

...patients with suspected community acqu...