Microbiological Laboratory Testing in the Diagnosis of Fungal Infections in Pulmonary and Critical Care Practice
Key Points
Key Points
- The rising prevalence of fungal infections is likely related to several factors, including an ever-growing population of susceptible patients.
- Furthermore, endemic mycoses continue to pose a threat to both immunocompetent and immunosuppressed individuals.
- Recent advances in laboratory diagnostics have evolved to assist the diagnosis of pulmonary fungal infections.
- These guidelines focus on the use of galactomannan (GM) antigen and PCR testing in the diagnosis of invasive pulmonary aspergillosis (IPA), (1➝3)-β-D-glucan (BDG) assays or invasive candidiasis (IC), and the use of antigen and antibody testing in the diagnosis of endemic mycoses.
Diagnosis
...gnosis...
...2. Recommendations...
...ive fungal diseas...
...patients with severe immune compromise, such...
...suspected of invasive fungal dise...
...ulmonary aspergillosis...
...with severe immune compromise, such as...
...ents with severe immune compromise...
...s with severe immune compromise, such as...
Candidiasis
...ally ill patients in whom there is clinical conc...
...toplasmosi...
...he ATS recommends the use of Histoplasma antige...
...suggests the use of Histoplasma serologies i...
Blastomycosi...
...ith appropriate geographic exposure a...
...atients with suspected blastomycosi...
...with suspected blastomycosis, particular...
...idioidomycosis...
...ts with appropriate geographic exposure an...
...tients with suspected coccidioidomycosis, p...
...s with suspected community acquired pneumo...