Treatment of Depression in Adults with Epilepsy

For mild depressive episodes, psychoeducation or psychotherapies are treatment alternatives to antidepressants. Where medication is used (wish/preference of the patient, positive experience of the patient with response to medication treatment in the past, moderate or severe episodes in the past or if initial non-pharmacological trials failed should be considered), SSRIs are first choice medications. (1, B)

For moderate to severe depressive episodes, SSRIs are first choice medications. (1, B)