Chemotherapy in Combination With Radiotherapy for Definitive-Intent Treatment of Stage II-IVA Nasopharyngeal Carcinoma
Key Points
Key Points
- Nasopharyngeal carcinoma (NPC) is uncommon in many jurisdictions but remains a significant public health problem in East and Southeast Asia, which accounted for more than 70% of the approximate 129,000 new diagnoses worldwide in 2018.
- NPC relies almost exclusively on (chemo-)radiotherapy to achieve disease control in most presentations, particularly in the definitive treatment of stage II to IVA disease.
Treatment
...atment
...r Patients with Stage II to IVA Nasophary...
....1For all nasopharyngeal carcinoma (NPC) pati...
...1.2For all NPC patients, both sequ...
...mendation 1.3For all NPC patients,...
...ion 1.4For all NPC patients, gross tumor volum...
...tion 1.5For NPC patients who have underg...
...ommendation 1.6The delineation of elective nod...
...emotherapy Sequen...
...on 2.1For T2N0 (AJCC 8th) NPC patients, c...
...2.2For T1-2N1 (AJCC 8th) NPC patients...
...2.3For Stage III–IVA (except T3N0) (AJCC 8th)...
...tion 2.4For Stage III–IVA (except T3N0) (AJC...
Recommendation 2.5For T3N0 (AJCC 8th) NPC pa...
...rrent Chemotherap...
...tion 3.1For all NPC patients without...
Recommendation 3.2For all NPC patients without...
...commendation 3.3For NPC patients with a...
...ndation 3.4For NPC patients with a contrain...
...on Chemotherapy...
...ndation 4.1For all NPC patients receiving inducti...
...4.2For NPC patients receiving induction chemo...
...n 4.3For NPC patients receiving induction...
...t Chemotherapy
...ecommendation 5.1For all NPC patients...
Recommendation 5.2For all NPC patients receivin...
...ommendation 5.3For all NPC patients recei...
...1. Stage II to IVA Nasopharyngeal Carcino...