Management of Adult Patients with Acute Respiratory Distress Syndrome

Publication Date: November 29, 2023

Key Points

Key Points

  • The acute respiratory distress syndrome (ARDS) is a life-threatening form of respiratory failure characterized by acute hypoxemia and bilateral radiographic infiltrates.
  • ARDS management remains largely supportive, high mortality rates persist, with those who survive often facing long-term impairments.
  • Since 2017, new data have emerged addressing multiple ARDS therapies and supportive care interventions that include corticosteroids, venovenous extracorporeal membrane oxygenation (VV-ECMO) neuromuscular blocking agents (NMBAs), and positive end expiratory pressure (PEEP), prompting an update to the guidelines.
  • This guideline updates and adds to recommendations for the management of patients with ARDS (Figure 1).

Treatment

Treatme...

...ndations in This Guideline...

...using corticosteroids for patients with AR...

...g venovenous extracorporeal membrane oxygenation...

...neuromuscular blockers in patients with e...

...using higher PEEP without lung recruitment mane...

...commend against using prolonged lung re...


...s From the 2017 Guideline That Remain in Place...

...commend using mechanical ventilation str...

...ne positioning for >12 hours per day i...

...mend against the routine use of high-freque...


...igure 1. Current ATS Guidelines for the Ma...


...tions and Practical Considerations...