Clinical Utility of Polygenic Risk Scores for Embryo Selection

Authoring Organization

Publication Month/Year

February 23, 2024

Last Updated Month/Year

March 13, 2024

Supplemental Implementation Tools

Document Type


Country of Publication


Inclusion Criteria

Female, Adult

Health Care Settings

Ambulatory, Outpatient

Intended Users

Nurse, nurse practitioner, physician, physician assistant


Assessment and screening


genetic testing, in vitro fertilization, embryo selection, polygenic risk score

Source Citation

Grebe TA, Khushf G, Greally JM, Turley P, Foyouzi N, Rabin-Havt S, Berkman BE, Pope K, Vatta M, Kaur S; ACMG Social, Ethical, and Legal Issues Committee. Clinical utility of polygenic risk scores for embryo selection: A points to consider statement of the American College of Medical Genetics and Genomics (ACMG). Genet Med. 2024 Feb 6:101052. doi: 10.1016/j.gim.2023.101052. Epub ahead of print. PMID: 38393332.