Treatment of Heart Failure With Reduced Ejection Fraction

Authoring Organization

Publication Month/Year

March 8, 2024

Last Updated Month/Year

March 13, 2024

Document Type


Country of Publication


Document Objectives

The purpose of this document is to update the 2021 ECDP with further data from recent studies and to provide succinct, practical guidance for managing patients with HFrEF. The format of the 10 Pivotal Issues in the prior versions of this ECDP was preserved, and their associated treatment algorithms and tables have been updated to accommodate the evolving evidence.

Inclusion Criteria

Male, Female, Adult, Older adult

Health Care Settings

Ambulatory, Outpatient

Intended Users

Nurse, nurse practitioner, physician, physician assistant


Diagnosis, Assessment and screening, Treatment, Management

Diseases/Conditions (MeSH)

D006333 - Heart Failure


heart failure, heart failure with reduced ejection fraction (HFrEF), HFrEF

Source Citation

Maddox, T, Januzzi, J. et al. 2024 ACC Expert Consensus Decision Pathway for Treatment of Heart Failure With Reduced Ejection Fraction: A Report of the American College of Cardiology Solution Set Oversight Committee. J Am Coll Cardiol. null2024, 0 (0) .

Supplemental Methodology Resources

Data Supplement