Vitamin D for Disease Prevention

Publication Date: June 3, 2024

Key Points

Key Points

  • Numerous studies demonstrate an association between serum concentrations of 25-hydroxyvitamin D (25[OH]D) and a variety of common disorders including musculoskeletal, metabolic, cardiovascular, malignant, autoimmune, and infectious diseases. This has led to widespread supplementation with vitamin D supplementation and increased laboratory testing for 25(OH)D in the general population.
  • The benefit-risk ratio of this increase in vitamin D supplementation is not clear, and the optimal vitamin D intake and serum 25(OH)D concentrations for disease prevention remain uncertain.
  • This guideline offers clinical guidelines for the use of vitamin D (cholecalciferol [vitamin D3] or ergocalciferol [vitamin D2]) to lower the risk of disease in individuals without established indications for vitamin D treatment or 25(OH) D testing.

Treatment

Treatment

...n Ages 1–18 Year...

...mendation 1...

...adolescents ages 1–18 years, we sugge...


...gnant Adults...

...ecommendation...

...adult population younger than age 50 years, we...

...ommendation 3...

...adult population younger than age 50 ye...


...ts Aged 50–74 Years...

...commendation 4

...eneral population ages 50 to 74 years,...

...mmendation 5

In the general population ages 50 to 74 years, w...


...s Aged ≥75 Year...

Recommendatio...

...neral population ages 75 years and older, we...

Recommendati...

...general population ages 75 years and older,...


...gnancy...

Recommendati...

...suggest empiric vitamin D supplementat...

...ecommendation...

...y, we suggest against routine 25(OH)D testing....


...With Prediabetes (By Glycemic Criteria)

...mmendation 10...

...dults with high-risk prediabetes,...


Dosi...

Recommendation 1...

...lts ages 50 years and older who have ind...


...althy Adult...

...commendation 12...

...n healthy adults, we suggest against routine s...


...lts with Dark Comple...

...ecommendation...

...with dark complexion, we suggest against routin...


...s with Obesit...

...mendation 14...

...adults with obesity, we suggest aga...