Vitamin D for Disease Prevention

Publication Date: June 3, 2024

Key Points

Key Points

  • Numerous studies demonstrate an association between serum concentrations of 25-hydroxyvitamin D (25[OH]D) and a variety of common disorders including musculoskeletal, metabolic, cardiovascular, malignant, autoimmune, and infectious diseases. This has led to widespread supplementation with vitamin D supplementation and increased laboratory testing for 25(OH)D in the general population.
  • The benefit-risk ratio of this increase in vitamin D supplementation is not clear, and the optimal vitamin D intake and serum 25(OH)D concentrations for disease prevention remain uncertain.
  • This guideline offers clinical guidelines for the use of vitamin D (cholecalciferol [vitamin D3] or ergocalciferol [vitamin D2]) to lower the risk of disease in individuals without established indications for vitamin D treatment or 25(OH) D testing.

Treatment

Treatment

...ren Ages 1–18 Years...

...ommendation 1...

...adolescents ages 1–18 years, we suggest em...


...onpregnant Ad...

...ecommendati...

...l adult population younger than age 5...

...commendation...

...general adult population younger than age...


...ged 50–74 Years...

Recommendat...

...n the general population ages 50 to 74 years, we...

...commendation 5...

...the general population ages 50 to 74 years, w...


...Aged ≥75 Years...

...ommendation 6

...population ages 75 years and older,...

...ommendation...

In the general population ages 75 years and older,...


...gnancy...

...mendation 8...

...empiric vitamin D supplementation during pre...

...commendation 9

...egnancy, we suggest against routine 25(OH)...


...dults With Prediabetes (By Glycemic Crit...

...ommendation 10

...th high-risk prediabetes, in addition to lifest...


...sing...

...ecommendation 11

...lts ages 50 years and older who have indicati...


...althy Adults...

Recommendation 12

In healthy adults, we suggest against r...


...ts with Dark Compl...

...mmendation 13...

...h dark complexion, we suggest against routine...


...with Obesity

...commendation 14...

...dults with obesity, we suggest against routine sc...