Vitamin D for Disease Prevention

Publication Date: June 3, 2024

Key Points

Key Points

  • Numerous studies demonstrate an association between serum concentrations of 25-hydroxyvitamin D (25[OH]D) and a variety of common disorders including musculoskeletal, metabolic, cardiovascular, malignant, autoimmune, and infectious diseases. This has led to widespread supplementation with vitamin D supplementation and increased laboratory testing for 25(OH)D in the general population.
  • The benefit-risk ratio of this increase in vitamin D supplementation is not clear, and the optimal vitamin D intake and serum 25(OH)D concentrations for disease prevention remain uncertain.
  • This guideline offers clinical guidelines for the use of vitamin D (cholecalciferol [vitamin D3] or ergocalciferol [vitamin D2]) to lower the risk of disease in individuals without established indications for vitamin D treatment or 25(OH) D testing.

Treatment

...eatment

...ldren Ages 1–18 Years...

Recommendat...

...adolescents ages 1–18 years, we...


...pregnant Adults

Recommendatio...

...ral adult population younger than age 50 y...

...ommendation...

...he general adult population younger than age...


...Aged 50–74 Years...

...ommendation...

...population ages 50 to 74 years, we suggest agai...

...ommendation 5...

In the general population ages 50 to...


Adults Aged ≥75...

...mmendation 6...

...the general population ages 75 years...

Recommendation...

...al population ages 75 years and older, we...


...regnancy...

...mendation 8...

We suggest empiric vitamin D supplementation...

...commendation 9

..., we suggest against routine 25(OH)D testing...


...Prediabetes (By Glycemic Criteria)...

Recommendation...

...high-risk prediabetes, in addition to lifestyle m...


...osing...

...commendation...

...ages 50 years and older who have indications...


...thy Adults...

Recommendation 12

...healthy adults, we suggest against rout...


...lts with Dark Complexi...

...ecommendatio...

...lts with dark complexion, we suggest a...


...ts with Obesity...

...ecommendation 14

...obesity, we suggest against routine...