Diagnosis of Pulmonary Hypertension

Publication Date: December 1, 2018
Last Updated: March 14, 2022

Diagnostic approach in patients with clinical suspicion for PH/pulmonary arterial hypertension

Established diagnostic tools


Since the US National Institutes of Health (NIH) registry report on primary PH in 1987, the ECG has been considered a reliable clue to the presence of PH.

Practice recommendations (including high-risk population screening recommendations)

Scleroderma (systemic sclerosis) and scleroderma spectrum

For patients with SSc and SSc spectrum with uncorrected DLCO 1.6 (assuming none-to-mild interstitial lung disease) and >2-fold upper limit of normal of NT-proBNP. If any of these screening tests are positive, these patients should be referred for RHC. For those with uncorrected DLCO ⩾80% of predicted, screening may be considered with TTE.



Diagnosis of Pulmonary Hypertension

Authoring Organization