Radiation Therapy for Cervical Cancer

Publication Date: June 1, 2020

Last Updated: March 14, 2022

Recommendations

Postoperative RT with or without systemic therapy

For women undergoing surgery for cervical cancer who have high surgicopathologic risk factors, adjuvant EBRT and concurrent platinum-based chemotherapy are recommended. (StrongHigh)

Implementation remark:
High-risk factors include positive margin(s) or positive lymph node(s) or extension into the parametrial tissue.

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For women with cervical cancer and intermediate-risk factors, adjuvant EBRT is recommended to decrease locoregional recurrence. (StrongHigh)

Implementation remark: Intermediate-risk factors include:
• LVSI plus deep one-third cervical stromal invasion with any tumor size
• LVSI plus middle one-third stromal invasion and tumor size ≥2 cm
• LVSI plus superficial one-third stromal invasion and tumor size ≥5 cm
• No LVSI but deep or middle one-third stromal invasion plus tumor size ≥4 cm

Radiation Therapy for Cervical Cancer

Recommendations

Postoperative RT with or without systemic therapy

Overview

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Authoring Organization