Diagnosis and Detection of Sarcoidosis
Publication Date: April 1, 2020
Last Updated: March 14, 2022
Diagnosis
Lymph Node Sampling
In patients for whom there is a high clinical suspicion for sarcoidosis (e.g., Löfgren’s syndrome, lupus pernio, or Heerfordt’s syndrome), the ATS suggests NOT sampling lymph nodes.
(C, VL)
Remarks: Patients who do not undergo lymph node sampling require close clinical follow-up.
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For patients presenting with asymptomatic, bilateral hilar lymphadenopathy, the ATS makes no recommendations for or against obtaining a lymph node sample.
(, )
Remarks: If lymph node sampling is not obtained, close clinical follow-up is a reasonable alternative approach.
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For patients with suspected sarcoidosis and mediastinal and/or hilar lymphadenopathy for whom it has been determined that tissue sampling is necessary, the ATS suggests endobronchial ultrasound (EBUS)-guided lymph node sampling, rather than mediastinoscopy, as the initial mediastinal and/or hilar lymph node sampling procedure. (C, VL)
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Title
Diagnosis and Detection of Sarcoidosis
Authoring Organization
American Thoracic Society