Management of Cancer Cachexia
July 12, 2023
Supplemental Implementation Tools
External Publication Status
Country of Publication
The purpose of this guideline is to provide evidence-based guidance on the optimal approach for the treatment of cachexia in patients with advanced cancer. Cachexia is a multifactorial syndrome characterized by loss of appetite, weight, and skeletal muscle, leading to fatigue, functional impairment, increased treatment-related toxicity, poor quality of life, and reduced survival.
Target Patient Population
Adult patients with advanced cancer and loss of appetite, body weight, and/or lean body mass (ie, skeletal muscle).
Target Provider Population
Clinicians who provide care to adult patients with cancer, as well as patients and caregivers.
Female, Male, Adult, Older adult
Health Care Settings
Ambulatory, Home health, Hospital, Long term care
Social worker, physician, health systems pharmacist, dietician nutritionist, nurse, nurse practitioner, physician assistant
D002100 - Cachexia
cancer, Cancer Cachexia, nutritional interventions, pharmacological interventions, precachexia, refractory cachexia, cachexia
Eric J. Roeland, MD; Kari Bohlke, ScD; Vickie E. Baracos, PhD; Management of Cancer Cachexia: ASCO Guideline update. J Clin Oncol. 2023 July 12. doi: 10.1200/JCO.23.01280
Eric J. Roeland, MD; Kari Bohlke, ScD; Vickie E. Baracos, PhD; Eduardo Bruera, MD; Egidio del Fabbro, MD; Suzanne Dixon, MPH, MS, RD; Marie Fallon, MD; Jørn Herrstedt, MD, DMSci; Harold Lau, MD; Mary Platek, PhD, MS, RD; Hope S. Rugo, MD; Hester H. Schnipper, LICSW; Thomas J Smith, MD; Winston Tan, MD; Charles L. Loprinzi, MD. Management of Cancer Cachexia: ASCO Guideline. J Clin Oncol. 2020 May 20 doi: 10.1200/JCO.20.00611