Diagnosis and Management of Squamous Cell Carcinoma of Unknown Primary in the Head and Neck
Key Points
Key Points
Preoperative Evaluation
Preoperative Evaluati...
...undergoing evaluation for a neck mass su...
...ne-Needle aspiration or core biopsy of a clin...
...h-risk human papillomavirus (HR-HPV) testing sh...
...ast enhanced computed tomography (CEC...
...mary is not evident on clinical examination and CE...
Diagnostic And Therapeutic Surgical Procedures
...And Therapeutic Surgical Procedures...
...Patients should undergo a complete...
...nts with unilateral lymphadenopathy, i...
...tients with bilateral lymphadenopathy, if a primar...
...s in whom the primary tumor is identified durin...
...e specimens from suspected primary sites (biops...
...traoperative frozen section of biopsies of s...
Surgical Considerations
...rgical Consideration...
...For small-volume bilateral neck disease...
....3: Large-volume bilateral neck disease,...
...ry surgery is planned, Levels IIA, III and...
...ral, small-volume neck disease, either definit...
Radiotherapy
Radiotherap...
...: Patients receiving radiotherapy or concurren...
...Patients treated with primary radiotherapy for un...
...Patients treated with primary radiotherap...
...patients presenting with clinical scenario...
...nts with a clinicopathologic presentation highly...
4.6: Patients treated with primary...
...to anatomic mucosal regions at risk,...
...ients treated with primary radiotherapy for...
...or patients treated with primary radio...
...ts receiving radiotherapy or concurr...
...ts for whom no primary site is pathologically i...
...juvant radiotherapy should not be administered...
...13: Adjuvant radiotherapy should be administered...
...radiation dose to the dissected regions...
Systemic Therapy
...mic Therapy
...nt administration of cisplatin with definiti...
...t administration of cisplatin with definitive radi...
...7: Concurrent administration of cisplatin to adj...
...nt administration of cisplatin with definitive rad...
Figure 1. Diagnosis & Management Algorithm of SCCUP in the Head and Neck
...agnosis & Management Algorithm of SCCUP...
Figure 2. Diagnosis & Management Algorithm of SCCUP in the Head and Neck (continued)
Figure 2. Diagnosis & Management Algorithm of...