Diagnosis and Management of Squamous Cell Carcinoma of Unknown Primary in the Head and Neck
Key Points
Key Points
Preoperative Evaluation
...Preop...
...ients undergoing evaluation for a neck m...
...Needle aspiration or core biopsy of a clin...
...uman papillomavirus (HR-HPV) testing should be...
...Contrast enhanced computed tomogra...
...imary is not evident on clinical exami...
Diagnostic And Therapeutic Surgical Procedures
...Di...
....1: Patients should undergo a complete operat...
...or patients with unilateral lymphadenopathy,...
...or patients with bilateral lymphadenopathy, if...
...: For patients in whom the primary t...
...ecimens from suspected primary sites (b...
...: Intraoperative frozen section of biop...
Surgical Considerations
...Surgic...
3.2: For small-volume bilateral neck disea...
...lume bilateral neck disease, and/or gross (mac...
...y surgery is planned, Levels IIA, III an...
...: For unilateral, small-volume neck disease,...
Radiotherapy
...Radiothe...
...ts receiving radiotherapy or concurren...
4.2: Patients treated with primary rad...
4.3: Patients treated with primary rad...
4.4: In patients presenting with clinical sce...
....5: In patients with a clinicopatholo...
...ents treated with primary radiotherapy f...
...7: In addition to anatomic mucosal regions a...
....8: Patients treated with primary radi...
...ents treated with primary radiotherapy, a biol...
...ients receiving radiotherapy or concurren...
...: Patients for whom no primary site...
...radiotherapy should not be administered to patie...
...Adjuvant radiotherapy should be admini...
...nt radiation dose to the dissected regions of...
Systemic Therapy
...Systemic The...
...oncurrent administration of cisplatin with...
...oncurrent administration of cisplatin with definit...
...nt administration of cisplatin to adjuvant radia...
...ent administration of cisplatin with definitive ra...
Figure 1. Diagnosis & Management Algorithm of SCCUP in the Head and Neck
...e 1. Diagnosis & Management Algorithm of SCCUP...
Figure 2. Diagnosis & Management Algorithm of SCCUP in the Head and Neck (continued)
...e 2. Diagnosis & Management Algorithm of SCCUP...