Diagnosis and Management of Squamous Cell Carcinoma of Unknown Primary in the Head and Neck
Key Points
Key Points
Preoperative Evaluation
...rative Evaluation...
...1: Patients undergoing evaluation for a n...
...le aspiration or core biopsy of a clinical...
...human papillomavirus (HR-HPV) testing should be d...
...Contrast enhanced computed tomography (CECT) of t...
...mary is not evident on clinical examination and CE...
Diagnostic And Therapeutic Surgical Procedures
...ic And Therapeutic Surgical Procedu...
...ts should undergo a complete operati...
...ts with unilateral lymphadenopathy, if a primary s...
...nts with bilateral lymphadenopathy, if a p...
...For patients in whom the primary tumor i...
...ecimens from suspected primary site...
...operative frozen section of biopsies of suspi...
Surgical Considerations
...ical Consideration...
...or unilateral, small-volume neck disease, eith...
...2: For small-volume bilateral neck...
3.3: Large-volume bilateral neck disease, an...
...n primary surgery is planned, Levels IIA...
Radiotherapy
Radiotherapy
...eceiving radiotherapy or concurrent...
....2: Patients treated with primary radiothe...
4.3: Patients treated with primary radiot...
...s presenting with clinical scenarios...
...ts with a clinicopathologic presentation highl...
...ients treated with primary radiotherapy f...
...: In addition to anatomic mucosal regions at risk...
...8: Patients treated with primary radiothera...
....9: For patients treated with prima...
...ents receiving radiotherapy or concurrent chem...
...nts for whom no primary site is pathologica...
...djuvant radiotherapy should not be administered t...
....13: Adjuvant radiotherapy should be admin...
....14: Adjuvant radiation dose to the dis...
Systemic Therapy
...emic Therapy...
...: Concurrent administration of cispla...
...urrent administration of cisplatin with definit...
...17: Concurrent administration of cisp...
...8: Concurrent administration of cisplatin with d...
Figure 1. Diagnosis & Management Algorithm of SCCUP in the Head and Neck
...Diagnosis & Management Algorithm of SCCUP...
Figure 2. Diagnosis & Management Algorithm of SCCUP in the Head and Neck (continued)
...iagnosis & Management Algorithm of SCCUP...