Role of Probiotics in the Management of Gastrointestinal Disorders

Publication Date: June 9, 2020

Key Points

Key Points

  • “Probiotics” are defined by the Food and Agriculture Organization of the United Nations and the World Health Organization as “live microorganisms which when administered in adequate amounts confer a health benefit on the host.”
  • “Prebiotics” are nutrients which promote growth or beneficial functions of beneficial microbes.
  • It is estimated that in 2015 3.9 million American adults used some form of probiotics or prebiotics.
  • The industry is largely unregulated, allowing widespread use and often biased information.
    • Clinical studies, mostly with small numbers of patients, have been extremely varied including differences in the strain(s), dose, and route of administration of microbe(s) used, the research methodology and the reporting of endpoints and outcomes.
  • This study prioritized Clostridioides difficile-associated diseases, inflammatory bowel disease, irritable bowel syndrome, infectious gastroenteritis, and necrotizing enterocolitis and is focused on patient-important outcomes.

Treatment

Treatmen...

...atients with C. difficile infection, AGA recomme...


...and children on antibiotic treatment, AG...


...In adults and children with Crohn’...


...and children with ulcerative colitis, AGA...


.... In adults and children with pouchitis, AGA...


...omatic children and adults with irr...


...In children with acute infectious gastroen...


.... In preterm (less than 37 weeks GA), low bir...