Role of Probiotics in the Management of Gastrointestinal Disorders

Publication Date: June 9, 2020

Key Points

Key Points

  • “Probiotics” are defined by the Food and Agriculture Organization of the United Nations and the World Health Organization as “live microorganisms which when administered in adequate amounts confer a health benefit on the host.”
  • “Prebiotics” are nutrients which promote growth or beneficial functions of beneficial microbes.
  • It is estimated that in 2015 3.9 million American adults used some form of probiotics or prebiotics.
  • The industry is largely unregulated, allowing widespread use and often biased information.
    • Clinical studies, mostly with small numbers of patients, have been extremely varied including differences in the strain(s), dose, and route of administration of microbe(s) used, the research methodology and the reporting of endpoints and outcomes.
  • This study prioritized Clostridioides difficile-associated diseases, inflammatory bowel disease, irritable bowel syndrome, infectious gastroenteritis, and necrotizing enterocolitis and is focused on patient-important outcomes.

Treatment

...atment...

...patients with C. difficile infection,...


...n adults and children on antibiotic treatment, AGA...


...and children with Crohn’s disease...


...lts and children with ulcerative colit...


...In adults and children with pouchiti...


...ptomatic children and adults with ir...


...In children with acute infectious gastro...


...ess than 37 weeks GA), low birth weight infants...