Obesity

Publication Date: January 2, 2015

Key Points

Key Points

  • The Task Force agrees with the opinion of prominent medical societies that current scientific evidence supports the view that obesity is a disease.
  • Weight loss produces many benefits including risk factor improvement, prevention of disease, and improvements in feeling and function. Greater weight loss produces greater benefits, but modest (5%–10%) weight loss, such as that produced by lifestyle modifications and medications, has been shown to produce significant improvements in many conditions.
  • Medications used for the management of conditions other than obesity can contribute to or exacerbate weight gain in susceptible individuals. Many of these conditions are also associated with obesity.
  • Health care providers can help patients prevent or attenuate weight gain by appropriately prescribing medications that would promote weight loss or minimize weight gain when treating these conditions.
  • Health care providers can help selected patients successfully lose weight and maintain lost weight by appropriately prescribing weight loss medications or in some cases surgical intervention as an adjunct to lifestyle change.

Diagnosis

...agnosis...

...auses of ObesityHaving trouble viewi...


Table 2. Comorbid Conditions in Ob...


Treatment

...eatment...

...Society (ES) recommends that diet, exercise, an...


...der to promote long-term weight maintenance, ES su...


...n patients with uncontrolled HTN or history of he...


...essment of efficacy and safety at least...


...ient’s response to a weight loss medicatio...


...ation for chronic obesity management...


...with T2DM who are overweight or obe...


...h CVD who seek pharmacological treat...


...That Cause Weight Gain and Some Alter...

...ommends weight-losing and weight-ne...

...ents with T2DM requiring insulin th...

...ACE inhibitors, angiotensin recepto...

...ant therapy is indicated, ES recomm...

...commends using weight-neutral antipsychotic alt...

...ecommends considering weight gain pote...

...th a BMI >27 kg/m2 with comorbidities or >30 kg/m2...

...monitoring the weight and waist circumfe...

...s the use of NSAIDs and disease-modifying anti...

...ests the use of antihistamines with less...


...f-Label Use of Drugs Approved for...

...ggests against the off-label use of medications...


.... Drugs Associated with Weight Gain and S...


Table 4. Advantages and Disadvantages Associ...


...Pharmacotherapy for Obesity in the United Stat...