Obesity

Publication Date: January 2, 2015

Key Points

Key Points

  • The Task Force agrees with the opinion of prominent medical societies that current scientific evidence supports the view that obesity is a disease.
  • Weight loss produces many benefits including risk factor improvement, prevention of disease, and improvements in feeling and function. Greater weight loss produces greater benefits, but modest (5%–10%) weight loss, such as that produced by lifestyle modifications and medications, has been shown to produce significant improvements in many conditions.
  • Medications used for the management of conditions other than obesity can contribute to or exacerbate weight gain in susceptible individuals. Many of these conditions are also associated with obesity.
  • Health care providers can help patients prevent or attenuate weight gain by appropriately prescribing medications that would promote weight loss or minimize weight gain when treating these conditions.
  • Health care providers can help selected patients successfully lose weight and maintain lost weight by appropriately prescribing weight loss medications or in some cases surgical intervention as an adjunct to lifestyle change.

Diagnosis

...Diagnosis...

...e 1. Causes of ObesityPrimary Causes...


...le 2. Comorbid Conditions in Obesit...


Treatment

...T...

...ety (ES) recommends that diet, exercise, an...


...er to promote long-term weight maintenan...


...n patients with uncontrolled HTN or his...


...s assessment of efficacy and safety...


...a patient’s response to a weight loss medicati...


...or chronic obesity management is prescribed...


...ients with T2DM who are overweight or obese...


...with CVD who seek pharmacological treatme...


...Drugs...

...ends weight-losing and weight-neutral...

...patients with T2DM requiring insulin therapy, ES...

...nds ACE inhibitors, angiotensin receptor b...

...tidepressant therapy is indicated, ES...

...ecommends using weight-neutral antipsychotic...

...considering weight gain potential in ch...

In women with a BMI >27 kg/m2 with...

...suggests monitoring the weight and waist circumfe...

...ests the use of NSAIDs and disease-modifying ant...

...ts the use of antihistamines with less central ne...


...Off-Label Use of Drugs A...

...s against the off-label use of medicati...


...3. Drugs Associated with Weight Gain and Sugg...


...Advantages and Disadvantages Associated with...


...harmacotherapy for Obesity in the United States...