ANCA-Associated Vasculitis
Publication Date: July 8, 2021
Key Points
Key Points
- Common clinical manifestations of granulomatosis with polyangiitis (GPA) include destructive sino-nasal lesions, pulmonary nodules, and pauci-immune glomerulonephritis.
- GPA is characterized histologically by necrotizing, granulomatous inflammation in addition to vasculitis.
- Common clinical manifestations of microscopic polyangiitis (MPA) include rapidly progressive pauci-immune glomerulonephritis and alveolar hemorrhage.
- MPA is characterized histologically by vasculitis without granulomatous inflammation.
- Common clinical manifestations of eosinophilic granulomatosis with polyangiitis (EGPA) include asthma, peripheral eosinophilia, and peripheral neuropathy.
- EGPA is characterized histologically by eosinophilic tissue infiltration in addition to vasculitis.
Definitions and Treatments
Recommendations
...Recommendations...
...atments: GPA, MPA, EGPA Treatments...
Table 4. Recommendations: GPA or MPA...
...Key Recommendations for the Treatment of Gra...
.... Recommendations: EGPA Remissi...
...y Recommendations for the Treatment of Eosinoph...