ANCA-Associated Vasculitis

Publication Date: July 8, 2021

Key Points

Key Points

  • Common clinical manifestations of granulomatosis with polyangiitis (GPA) include destructive sino-nasal lesions, pulmonary nodules, and pauci-immune glomerulonephritis.
    • GPA is characterized histologically by necrotizing, granulomatous inflammation in addition to vasculitis.
  • Common clinical manifestations of microscopic polyangiitis (MPA) include rapidly progressive pauci-immune glomerulonephritis and alveolar hemorrhage.
    • MPA is characterized histologically by vasculitis without granulomatous inflammation.
  • Common clinical manifestations of eosinophilic granulomatosis with polyangiitis (EGPA) include asthma, peripheral eosinophilia, and peripheral neuropathy.
    • EGPA is characterized histologically by eosinophilic tissue infiltration in addition to vasculitis.

Definitions and Treatments

Definitions and Tre...

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Recommendations

Recommenda...

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...Recommendations for the Treatment of Granu...


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...Key Recommendations for the Treatment of E...