Acute Hematogenous Osteomyelitis
Key Points
Key Points
- Acute hematogenous osteomyelitis (AHO) occurs when bacteria enter and proliferate within the cellular and extracellular matrix of bone, generally accompanied by a host inflammatory response.
- The incidence of AHO in children ranges from 1.2 to 13 cases per 100,000 children per year
- Most of the cases involve a single bone, but about 5% involve multiple bones.
- The presentation of AHO varies from well-localized infection over a single metaphysis with a minimal associated systemic inflammatory response to multifocal infection with septic shock.
- Fever and pain are the most common manifestations of bone infection.
Surveillance and Remediation
...Remediation Acute osteomyelitis...
Diagnosis
...agnosis...
...ratory Tests...
...n children with suspected AHO, we recommend perfo...
...ldren with suspected AHO, we suggest performi...
...th suspected AHO, we suggest against usin...
...Diagnosis Infection of adjacent soft tissu...
...asive Procedures In children with suspected A...
Imaging
...ldren with suspected AHO, we recommend...
...dren with suspected AHO requiring further imaging...
Treatment
...eatment...
...mpiric Antimicrobial The...
...th presumed AHO who are ill-appeari...
...dren with presumed AHO who are not clinicall...
...with suspected AHO, we recommend using...
...itive Parenteral and Oral Thera...
...n children with confirmed AHO, selection o...
...ren with suspected AHO without an identified...
...with AHO requiring a surgical procedure, we re...
...sive Therapeutic Procedures
...ren with AHO who present with sepsis or have...
...ld with AHO who is clinically stabl...
...ess the ResponseIn children with suspected...
...rge Planning
For children with suspected or docum...
...r children with suspected or documented AHO who...
...uration of AntibioticsIn children with AHO pres...
...-Therapy Imaging...
...ecommend against obtaining end-of-t...
...gainst routine end-of-therapy plain...
...th complicated AHO or with involvement of the...
...onresponse or Rel...
...children either experiencing primary treatme...
...should reassess the need for surgical inte...
...ong-Term Follow-upIn children with AHO who are d...
...iotic Choice and Duration of Therapy for Uncompl...
...otic Dosages for Pediatric Acute H...