Acute Hematogenous Osteomyelitis
Key Points
Key Points
- Acute hematogenous osteomyelitis (AHO) occurs when bacteria enter and proliferate within the cellular and extracellular matrix of bone, generally accompanied by a host inflammatory response.
- The incidence of AHO in children ranges from 1.2 to 13 cases per 100,000 children per year
- Most of the cases involve a single bone, but about 5% involve multiple bones.
- The presentation of AHO varies from well-localized infection over a single metaphysis with a minimal associated systemic inflammatory response to multifocal infection with septic shock.
- Fever and pain are the most common manifestations of bone infection.
Surveillance and Remediation
...ance and Remediation Acute osteomyel...
Diagnosis
...gnosis
Laboratory T...
...children with suspected AHO, we recommend perf...
...hildren with suspected AHO, we suggest pe...
...en with suspected AHO, we suggest against using s...
...fferential Diagnosis Infection of ad...
...ive Procedures In children with susp...
...aging...
...hildren with suspected AHO, we recommend obtaini...
...children with suspected AHO requiring...
Treatment
Treatment
...ntimicrobial Therapy...
...hildren with presumed AHO who are i...
...ildren with presumed AHO who are not...
...with suspected AHO, we recommend using empiric a...
...ive Parenteral and Oral Therapy...
...dren with confirmed AHO, selection of a d...
...n with suspected AHO without an id...
...AHO requiring a surgical procedure, we recom...
...vasive Therapeutic Proc...
...ith AHO who present with sepsis or have a rapi...
...hild with AHO who is clinically sta...
...ss the ResponseIn children with suspect...
...arge Planning...
...ildren with suspected or documented AHO...
...th suspected or documented AHO who respon...
...uration of AntibioticsIn children with...
...of-Therapy Imagi...
...we recommend against obtaining end-of-...
...against routine end-of-therapy plain...
...ildren with complicated AHO or with involvemen...
...sponse or Relapse...
...dren either experiencing primary treatment...
...ld reassess the need for surgical intervention...
...ong-Term Follow-upIn children with AHO wh...
...Antibiotic Choice and Duration of Therapy for...
...Antibiotic Dosages for Pediatric A...