Management of Medullary Thyroid Carcinoma

Publication Date: June 3, 2015
Last Updated: October 9, 2023

Diagnosis

The current ATA risk categories for hereditary MTC should be changed. ( C )
  • The current level D category should be changed to a new category, “highest risk” (HST), that includes patients with MEN2B and the RETcodon M918T mutation.
  • The current level C category should be changed to a new category, “high risk” (H), that includes patients with MEN 2A and RETcodon C634 mutations.
  • The current level A and B categories should be combined into a new category “moderate risk” (MOD) that includes patients with hereditary MTC and RETcodon mutations other than M918T and C634.
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Treatment

Patients with MTC and no evidence of neck lymph node metastases by US examination and no evidence of distant metastases should have a total thyroidectomy and dissection of the lymph nodes in the central compartment (level VI). ( B )
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Overview

Title

Management of Medullary Thyroid Carcinoma

Authoring Organization