Diagnosis, Risk Stratification, And Management Of Pulmonary Hypertension Of Sickle Cell Disease.
Publication Date: March 5, 2014
Key Points
Key Points
Pulmonary hypertension (PH) and right heart failure are well-established risk factors for mortality in sickle cell disease (SCD).
Observational studies have consistently shown that increased tricuspid regurgitant jet velocity (TRV) measured by Doppler echocardiography, an increased serum N-terminal pro–brain natriuretic peptide (NT-pro-BNP) level, and pulmonary hypertension measured by right heart catheterization are all independent risk factors for mortality in adults.
To reduce the variability and to improve the quality of care that patients with SCD receive, the ATS developed clinical practice guidelines to advise hematologists, pulmonologists, cardiologists, pediatricians, and internists about how to identify and manage patients with SCD who are at increased risk for mortality.
Observational studies have consistently shown that increased tricuspid regurgitant jet velocity (TRV) measured by Doppler echocardiography, an increased serum N-terminal pro–brain natriuretic peptide (NT-pro-BNP) level, and pulmonary hypertension measured by right heart catheterization are all independent risk factors for mortality in adults.
To reduce the variability and to improve the quality of care that patients with SCD receive, the ATS developed clinical practice guidelines to advise hematologists, pulmonologists, cardiologists, pediatricians, and internists about how to identify and manage patients with SCD who are at increased risk for mortality.
Diagnosis
Diagno...
...ification guides clinical decision ma...
...eased risk for mortality is defined as a T...
...1. Sample Questions for Evaluation of Dyspnea...
...e 1. Proposed Algorithm for Evaluation of Pulmona...
...hocardiogram of a Patient with Pulmonary Hypert...
Treatment
...eatmen...
For patients with SCD who have an increased risk...
...with SCD who have an increased risk for mo...
...atients with SCD who have RHC-confirmed PH...
...or all patients with SCD who have elevated...
...most patients with SCD who have RHC-conf...
...ect patients with SCD who have RHC-confirmed marke...
For patients with SCD who have RHC-confirmed...
...ationsHaving trouble viewing table? Expan...