Diagnosis of Idiopathic Pulmonary Fibrosis
Key Points
Key Points
Rarely, middle-aged adults (>40 yr and <60 yr), especially those with risks for familial pulmonary fibrosis, may otherwise manifest the same clinical scenario as the typical patient older than 60 years.
The recommendations in this guideline are for the patterns and distributions of images obtained by high-resolution CT (HRCT) imaging and, thus, require that patients be subjected to HRCT of the chest for evaluation.
Diagnosis
...Diagnos...
...iagnostic Criteria for IPF Exclusion of o...
...Table 1. Compar...
...L cellular ana...
...n of Probable UIP, Indeterminate for U...
...Pattern of UIP: We suggest NOT performing BAL ce...
...al lung biopsy...
...n of Probable UIP, Indeterminate for UI...
...Pattern of UIP: We recommend NOT per...
...onchial lung biopsy...
...Pattern of Probable UIP, Indeterminate for UIP, a...
...ttern of UIP: We recommend NOT p...
Lung cryobiops...
...ern of Probable UIP, Indeterminate for UIP, a...
...rn of UIP: We recommend NOT performin...
Medical history of medication use and envir...
...gical testing to exclude connective tissue...
...iplinary discussionWe suggest multi...
...rkersWe recommend NOT measuring serum MM...
...Resolution CT Scanning ParametersHaving trouble v...
...e 3. High-Resolution CT Scanning Patterns Having...
...esolution CT Images Demonstrating a Usual Int...
...Probable UIP Pattern(A–C) Transv...
...igure 3. Indeterminate for UIP Pattern (early UI...
...ndeterminate for UIP Pattern ...
...tern Suggestive of an Alternative Diagnosis fo...
...gure 6. Acute Exacerbation of IPF(A...
...ure 7. Histopathology Demonstrating UIP(A) Low-...
...able 4. Histopathology Patterns and Features Havi...
...IPF Diagnosis Based Upon HRCT and Biopsy...
...9. Diagnostic Algorithm for IPF...