Diagnosis of Idiopathic Pulmonary Fibrosis
Key Points
Key Points
Rarely, middle-aged adults (>40 yr and <60 yr), especially those with risks for familial pulmonary fibrosis, may otherwise manifest the same clinical scenario as the typical patient older than 60 years.
The recommendations in this guideline are for the patterns and distributions of images obtained by high-resolution CT (HRCT) imaging and, thus, require that patients be subjected to HRCT of the chest for evaluation.
Diagnosis
...Diagnosis...
...eria for IPF Exclusion of other known caus...
...Table 1. Comparison...
...llular analysis...
...Probable UIP, Indeterminate for UIP, and A...
...Pattern of UIP: We suggest NOT per...
...urgical lung biops...
...n of Probable UIP, Indeterminate fo...
...n of UIP: We recommend NOT performing surgi...
...sbronchial lung biop...
...of Probable UIP, Indeterminate for UI...
...T Pattern of UIP: We recommend NOT per...
Lung cryobio...
...attern of Probable UIP, Indeterminate for UIP, a...
...n of UIP: We recommend NOT perfo...
...history of medication use and environmental...
...rological testing to exclude connective tissue...
...tidisciplinary discussionWe suggest multidi...
...rsWe recommend NOT measuring serum MMP-7, SP...
...2. High-Resolution CT Scanning Par...
...solution CT Scanning Patterns ...
...igure 1. High-Resolution CT Images...
...ure 2. Probable UIP Pattern (A–C) Tran...
...gure 3. Indeterminate for UIP Pattern (early...
...Indeterminate for UIP Pattern ...
...CT Pattern Suggestive of an Alternative...
...re 6. Acute Exacerbation of IPF (A...
...Histopathology Demonstrating UIP (A) Low-magnific...
...le 4. Histopathology Patterns and Features ...
...gure 8. IPF Diagnosis Based Upon HRCT and Biopsy P...
...Diagnostic Algorithm for IPF...