Noninvasive Ventilation For Acute Respiratory Failure

Publication Date: August 1, 2017
Last Updated: December 16, 2022


COPD Exacerbation

Bilevel NIV may be considered in COPD patients with an acute exacerbation in three clinical settings:
  1. To prevent acute respiratory acidosis — i.e., when the arterial CO2 tension (PaCO2) is normal or elevated but pH is normal.
  2. To prevent endotracheal intubation and invasive mechanical ventilation in patients with mild to moderate acidosis and respiratory distress, with the aim of preventing deterioration to a point when invasive ventilation would be considered.
  3. As an alternative to invasive ventilation in patients with severe acidosis and more severe respiratory distress.
Bilevel NIV may also be used as the only method for providing ventilatory support in patients who are not candidates for or decline invasive mechanical ventilation.



Noninvasive Ventilation For Acute Respiratory Failure

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