Severe Asthma Management
Publication Date: October 1, 2019
Key Points
Key Points
Following the recent appearance of new anti-interleukin biologic agents and standardization of sputum eosinophil counts and exhaled nitric oxide fraction (FENO), ATS/ERS have added recommendations for these agents for adults with severe uncontrolled asthma and modified certain other recommendations from the 2014 guideline.
Treatment
...reatmen...
...1. Recommendations for the Management o...
...suggest an anti-IL-5 strategy as add-on therapy...
...a blood eosinophil cut-point ≥150 Â...
...ing a blood eosinophil cut-off ≥260 µL−1 to...
...sing a FENO cut-off ≥19.5 ppb to identify ado...
...children, adolescents and adults with s...
...e suggest a trial of macrolide treatmen...
...against the use of chronic macroli...
...umab as add-on therapy for adult patients with s...
...onal Antibodies for Severe AsthmaHa...