Severe Asthma Management
Publication Date: October 1, 2019
Key Points
Key Points
Following the recent appearance of new anti-interleukin biologic agents and standardization of sputum eosinophil counts and exhaled nitric oxide fraction (FENO), ATS/ERS have added recommendations for these agents for adults with severe uncontrolled asthma and modified certain other recommendations from the 2014 guideline.
Treatment
Treatme...
...able 1. Recommendations for the Manag...
...suggest an anti-IL-5 strategy as add-on...
...hat a blood eosinophil cut-point ≥150...
...a blood eosinophil cut-off ≥260 µ...
We suggest using a FENO cut-off ≥19.5 ppb to ide...
...adolescents and adults with severe asthma unc...
...a trial of macrolide treatment to reduce a...
...nst the use of chronic macrolide trea...
...ggest dupilumab as add-on therapy fo...
...lonal Antibodies for Severe AsthmaHaving troub...