Severe Asthma Management

Publication Date: October 1, 2019

Key Points

Key Points

Following the recent appearance of new anti-interleukin biologic agents and standardization of sputum eosinophil counts and exhaled nitric oxide fraction (FENO), ATS/ERS have added recommendations for these agents for adults with severe uncontrolled asthma and modified certain other recommendations from the 2014 guideline.

Treatment

...reatmen...

...Recommendations for the Management...

...e suggest an anti-IL-5 strategy as ad...

We suggest that a blood eosinophil cut-point...

...t using a blood eosinophil cut-off ≥260...

...using a FENO cut-off ≥19.5 ppb to...

...n, adolescents and adults with sev...

...trial of macrolide treatment to reduce asthma e...

...suggest against the use of chronic mac...

We suggest dupilumab as add-on therapy...


...onoclonal Antibodies for Severe AsthmaHaving troub...