Use of Endocrine Therapy for Breast Cancer Risk Reduction
Introduction
Introduction
Diagnosis
Diagnosis
...east Cancer Risk Assessment ToolsHaving tro...
Treatment
...atment...
...2. Summary of All Recommendation...
Tamoxi...
...ssed as an option to reduce the risk of inva...
...OT recommended for use in women with a his...
...NOT recommended for women who are pregn...
Is NOT recommended in combination with h...
...should include a timely work-up of abnorma...
...sions with patients and health care provid...
...orally for 5 years. (EB, S)7251...
...idence-based on 5 RCTs with low risk of...
...aloxifen...
...cussed as an option to reduce the risk of invas...
...used longer than 5 years in women with ost...
...used for BC risk reduction in premenopausal women....
...OT recommended for use in women with a hist...
...ns with patients and health care providers should...
...60 mg/d orally for 5 years. (EB, S)7251...
...idence-based on 4 RCTs with low ris...
...mestane
...e discussed as an alternative to tamox...
...ed for BC risk reduction in premenopausal wom...
...ions with patients and health care provi...
...d orally for 5 years. (EB, M)7251...
...oderate evidence-based on 1 RCT with low ris...
...nastrozole
...mg/day orally for 5 years) should be disc...
...y to benefit are those with one of mo...
...nicians should NOT prescribe anastrozole, exemest...
...ween patients and health care providers should...
...or to initiating an aromatase inhibitor, cl...
...ans should inform women also of the possibility...
...igh harms; Evidence quality: high;...
Table 3. Summary of Agent Indication...
...Adverse Effects of Endocrine TherapyHaving troubl...