Use of Endocrine Therapy for Breast Cancer Risk Reduction
Introduction
Introduction
Diagnosis
...Diagnosis...
...east Cancer Risk Assessment ToolsHavin...
Treatment
...Treatme...
...Table 2. Summary of...
...Tamox...
...discussed as an option to reduce t...
...mended for use in women with a history of deep v...
...nded for women who are pregnant, women who may b...
...NOT recommended in combination with...
...llow-up should include a timely work-up of...
...ns with patients and health care providers should...
...SAGE: 20 mg/d orally for 5 years. (EB,...
...Strong evidence-based on 5 RCTs with low risk of b...
...Raloxifene...
...ussed as an option to reduce the risk of in...
...be used longer than 5 years in wom...
...d NOT be used for BC risk reduction in premen...
...T recommended for use in women with a history of...
...cussions with patients and health care provider...
DOSAGE: 60 mg/d orally for 5 yea...
...e-based on 4 RCTs with low risk of bias)...
...Exemestane...
...be discussed as an alternative to tamoxifen...
...OT be used for BC risk reduction in...
...patients and health care providers sh...
...mg/d orally for 5 years. (EB, M)7...
(Moderate evidence-based on 1 RCT with low risk...
...Anastrozole...
...e (1 mg/day orally for 5 years) should be d...
...n most likely to benefit are those with one of...
...icians should NOT prescribe anastrozole, exe...
...cussions between patients and health ca...
...ting an aromatase inhibitor, clinicians should...
...linicians should inform women also...
...weigh harms; Evidence quality: high;...
...of Agent IndicationsHaving trouble vi...
...Effects of Endocrine TherapyHaving troubl...