Germline and Somatic Tumor Testing in Epithelial Ovarian Cancer
Publication Date: January 27, 2020
Key Points
Key Points
- It is estimated that there will be 22,530 new cases of ovarian cancer diagnosed in 2019 in the United States and, in spite of advances in treatment, an estimated 13,980 women will die from the disease.
- Ovarian cancer ranks fifth in cancer deaths among women.
- Approximately 25% of all ovarian cancers are caused by a heritable genetic condition.
- Many medical societies recommend genetic testing for all women diagnosed with ovarian cancer, yet only about 30% of women undergo any genetic testing.
Diagnosis
...iagnosis...
...1.1All women diagnosed with epithe...
...ecommendation 1.2Women diagnosed with clear...
...dation 1.3Testing for dMMR may be offe...
...tion 1.4Those genetic evaluations should be co...
...endation 1.5First- or second-degree blood rela...
...ecommendation 2.1Women diagnosed w...
Recommendation 2.2Women diagnosed with recurre...
...2.3No recommendations can be made sup...
...endation 2.4Clinical decisions should not be bas...
...commendation 3.1Women with epitheli...
...ecommendation 3.2Women with epitheli...
...able 1. Definition of TermsHaving trouble...