Germline and Somatic Tumor Testing in Epithelial Ovarian Cancer

Publication Date: January 27, 2020

Key Points

Key Points

  • It is estimated that there will be 22,530 new cases of ovarian cancer diagnosed in 2019 in the United States and, in spite of advances in treatment, an estimated 13,980 women will die from the disease.
  • Ovarian cancer ranks fifth in cancer deaths among women.
  • Approximately 25% of all ovarian cancers are caused by a heritable genetic condition.
  • Many medical societies recommend genetic testing for all women diagnosed with ovarian cancer, yet only about 30% of women undergo any genetic testing.

Diagnosis

...agnosis

...tion 1.1All women diagnosed with epithelial ovar...


Recommendation 1.2Women diagnosed with...


...mendation 1.3Testing for dMMR may be offered...


...on 1.4Those genetic evaluations should be c...


...ion 1.5First- or second-degree blood relativ...


Recommendation 2.1Women diagnosed with epithelia...


...mendation 2.2Women diagnosed with recurrent...


...on 2.3No recommendations can be made suppor...


...n 2.4Clinical decisions should not be based o...


...ecommendation 3.1Women with epitheli...


...ion 3.2Women with epithelial ovarian cancer wh...


...tion of TermsHaving trouble viewing table?...