Germline and Somatic Tumor Testing in Epithelial Ovarian Cancer

Publication Date: January 27, 2020

Key Points

Key Points

  • It is estimated that there will be 22,530 new cases of ovarian cancer diagnosed in 2019 in the United States and, in spite of advances in treatment, an estimated 13,980 women will die from the disease.
  • Ovarian cancer ranks fifth in cancer deaths among women.
  • Approximately 25% of all ovarian cancers are caused by a heritable genetic condition.
  • Many medical societies recommend genetic testing for all women diagnosed with ovarian cancer, yet only about 30% of women undergo any genetic testing.

Diagnosis

...iagnosis...

...dation 1.1All women diagnosed with epithel...


...n 1.2Women diagnosed with clear cell, endometrioid...


...ation 1.3Testing for dMMR may be offered to wom...


...ndation 1.4Those genetic evaluations s...


...commendation 1.5First- or second-degree bloo...


...2.1Women diagnosed with epithelial ovari...


...2.2Women diagnosed with recurrent epithelial o...


Recommendation 2.3No recommendations ca...


...endation 2.4Clinical decisions should not be bas...


...endation 3.1Women with epithelial ovar...


...ion 3.2Women with epithelial ovari...


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