Treatment of Patients with Late-Stage Colorectal Cancer

Publication Date: March 9, 2020
Last Updated: November 8, 2022

Treatment

Recommendations on Symptom Management 

1.1 Patients with advanced-stage colorectal cancer

Clinicians should provide symptom control and establish a management plan with multi-disciplinary approach (ASCO Resource Levels: Basic, Limited, Enhanced, Maximal) (S)
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1.2 Patients with clinically unstable disease due to bowel obstruction or uncontrolled bleeding or uncontrolled pain

Surgical evaluation (ASCO Resource Levels: Basic, Limited, Enhanced, Maximal) (S)
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1.3 Patients with clinically unstable disease due to bowel obstruction or uncontrolled bleeding or uncontrolled pain

If resectable, and urgent surgery required due to obstruction or bleeding: surgery of primary tumor (ASCO Resource Levels: Basic, Limited, Enhanced, Maximal). (S)
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1.4 Patients with clinically unstable disease due to bowel obstruction or uncontrolled bleeding or uncontrolled pain

If unresectable, unable to do biopsy due to clinical scenario, go to ASCO Palliative Care Guidelines (ASCO Resource Levels: Basic, Limited, Enhanced, Maximal) (S)
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1.5 Patients with clinically stable disease with ongoing bleeding from primary site

Transfusion + surgery of primary tumor (ASCO Resource Levels: Basic, Limited) (S)
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Transfusion + multi-disciplinary specialized evaluation (ASCO Resource Levels: Enhanced, Maximal) (S)
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Overview

Title

Treatment of Patients with Late-Stage Colorectal Cancer

Authoring Organization

American Society of Clinical Oncology