Biomarkers for Adjuvant Endocrine and Chemotherapy in Early-Stage Breast Cancer
Key Points
Key Points
Diagnosis
...agnosis...
...ER-positive, HER2-negative Breast Cancer...
...(21-gene recurrence score)...
...n 1.1If a patient has node-negative breast cance...
...ommendation 1.2In the group of patie...
...mendation 1.3In the group of patie...
...1.4If a patient is postmenopausal and ha...
...on 1.5In the group of patients in Re...
...ion 1.6If a patient is premenopausal and has nod...
...ndation 1.7If a patient has node-positive bre...
...maPrint (70-gene sign...
Recommendation 1.8If a patient is ol...
...dation 1.9If a patient is 50 years of ag...
...1.10If a patient has low clinical risk, regar...
...commendation 1.11If a patient has node-po...
...ct (12-gene risk score)...
...n 1.12If a patient is postmenopausal and has bre...
...1.13If a patient is premenopausal...
...commendation 1.14If a patient has bre...
...signa (PAM50...
...dation 1.15If a patient is postmenopausal and h...
...mendation 1.16If a patient is premenop...
...mmendation 1.17If a patient is postmenopaus...
...ion 1.18If a patient has node-positive breast ca...
...mmostrat...
...re is insufficient evidence to rec...
...ancer Index (BCI)...
...t has ER-positive, HER2-negative, node-neg...
...tient has ER-positive, HER2-negative, node-p...
...i67
...ommendation 1.19If a patient is pos...
...ecommendation 1.20If a patient is postmenopausal a...
...n 1.21Despite the limitations associat...
...mmunohistochemistry 4 (...
...ndation 1.22If a patient has node-ne...
...PA and PAI-...
...a patient has ER-positive, HER2-negative (node-...
...s HER2-positive breast cancer or triple-negative b...
...ocrine Therapy For ER Receptor-positive HER...
...ncotype DX, EndoPredict, Prosigna, Ki67, or IHC4...
...on 1.23If a patient has node-negative b...
...CI
....24If a patient has node-negative o...
...dation 1.25If a patient has node-po...
...cal Treatment Score post-5 Years (CTS5)...
...1.26If a patient is postmenopausal and had in...
...ve Breast Cancer or TNBC...
...doPredict, MammaPrint, BCI, Prosig...
...n 1.27If a patient has HER2-positive breast canc...
...erging Biomarkers...
...-Infiltrating Lymphocytes (TILs)...
...on 1.28If a patient has node-negative or node-p...
PD-L1 Testin...
Recommendation 1.29If a patient has...
...ulating Tumor Cells (CT...
...mmendation 1.30If a patient has node...
...ting Tumor DNA (ctDNA)...
...ndation 1.31If a patient has node-negative o...
...east Cancer Biomarkers to Guide Adjuvant...
...lgorithm on Biomarkers to Guide Decisions on...
...assification of Patients According to...
...ASCO believes that cancer clinical trials are vit...