Adjuvant Therapy for Stage III Colon Cancer

Publication Date: April 15, 2019

Key Points

Key Points

In 2018, approximately 97,000 people living in the United States will be diagnosed with colon cancer. Of these patients, just less than one-third will have stage III disease, characterized by spread to regional lymph nodes and absence of distant metastases.

The primary treatment option for patients with stage III colon cancer is resection with curative intent, however recurrence rates can be as high as 50–80% with surgery alone.

Adjuvant chemotherapy is recommended to improve overall survival for patients who have a high risk of recurrence.

Treatment

Treatmen...

...patients with stage III resected colon cancer...

...with high risk (T4 and/or N2) stage III rese...

For patients with low risk (T1, T2, or T3 and N1)...

...shared decision-making approach should be used...


...of Key Evidence from the International Dur...


...xploratory subgroup analyses by risk of recurrenc...


...respecified subgroup analysis by type...