Management of the Neck in Squamous Cell Carcinoma of the Oral Cavity and Oropharynx
Key Points
Key Points
Oral SCC is predominately associated with tobacco and betel nut use. On the other hand, SCCOP is increasing in incidence in recent decades due to chronic latent infections of the human papillomavirus (HPV) and appears to disproportionately affect younger people.
The majority of patients with SCCOP have node-positive (cN+) necks at presentation, and 10-40% of patients without cN+ necks at presentation will have occult nodal metastases in both SCCOC and SCCOP. As such, management of the neck is a critical component of high quality oncologic care of these patients.
Treatment
...eatment...
...ral Cavit...
...r patients with oral cavity SCC classified as...
...ents with oral cavity SCC classifie...
...patients with a cN0 neck, an ipsilateral...
...ts with a cN+ contralateral neck, a contrala...
...therapeutic selective neck dissection for a...
...ant neck radiotherapy should NOT be administere...
...diotherapy should be administered to patien...
...nt neck radiotherapy should be administe...
...moradiotherapy using intravenous bol...
...rent weekly cisplatin may be administered wit...
...ve neck dissection is the preferred approach f...
...have undergone ipsilateral neck di...
...opharyn...
...ents with lateralized oropharyngeal carcinoma who...
...nts with lateralized oropharyngeal cancer who h...
...ents with tumors extending to the midli...
...urgical approach should be offered to patients w...
...h biopsy-proven distant metastases shou...
...T scan at ≥12 weeks after completi...
...who complete radiation/chemoradiation and have...
...PET/CT scan at ≥12 weeks shows mild FDG uptake...
...atment Algorithm for Management of the Neck in P...
Figure 2. Treatment Algorithm for Ma...