Management of the Neck in Squamous Cell Carcinoma of the Oral Cavity and Oropharynx
Key Points
Key Points
Oral SCC is predominately associated with tobacco and betel nut use. On the other hand, SCCOP is increasing in incidence in recent decades due to chronic latent infections of the human papillomavirus (HPV) and appears to disproportionately affect younger people.
The majority of patients with SCCOP have node-positive (cN+) necks at presentation, and 10-40% of patients without cN+ necks at presentation will have occult nodal metastases in both SCCOC and SCCOP. As such, management of the neck is a critical component of high quality oncologic care of these patients.
Treatment
...Treatment
...Oral...
...h oral cavity SCC classified as cT2-cT4, cN0...
...ents with oral cavity SCC classifi...
...ients with a cN0 neck, an ipsilateral el...
...n patients with a cN+ contralateral neck,...
...al therapeutic selective neck dissection...
...radiotherapy should NOT be administ...
...k radiotherapy should be administered to patien...
...vant neck radiotherapy should be admin...
...oradiotherapy using intravenous bolus c...
...kly cisplatin may be administered wit...
...e neck dissection is the preferred approac...
...ts who have undergone ipsilateral neck dissectio...
...Orophar...
...lateralized oropharyngeal carcinoma who...
...lateralized oropharyngeal cancer who h...
...ts with tumors extending to the midline t...
...urgical approach should be offered...
...ith biopsy-proven distant metastases should...
...can at ≥12 weeks after completion...
...atients who complete radiation/chemoradiation an...
...scan at ≥12 weeks shows mild FDG u...
...eatment Algorithm for Management of the Neck...
...gure 2. Treatment Algorithm for Man...