Management of the Neck in Squamous Cell Carcinoma of the Oral Cavity and Oropharynx
Key Points
Key Points
Oral SCC is predominately associated with tobacco and betel nut use. On the other hand, SCCOP is increasing in incidence in recent decades due to chronic latent infections of the human papillomavirus (HPV) and appears to disproportionately affect younger people.
The majority of patients with SCCOP have node-positive (cN+) necks at presentation, and 10-40% of patients without cN+ necks at presentation will have occult nodal metastases in both SCCOC and SCCOP. As such, management of the neck is a critical component of high quality oncologic care of these patients.
Treatment
Treatm...
Oral Cav...
For patients with oral cavity SCC classified...
...nts with oral cavity SCC classified as cT1,...
...patients with a cN0 neck, an ipsilateral ele...
...ents with a cN+ contralateral neck, a contralatera...
...teral therapeutic selective neck dissec...
...diotherapy should NOT be administered to patients...
...neck radiotherapy should be administ...
...djuvant neck radiotherapy should be administered...
...uvant chemoradiotherapy using intravenous bolus...
...t weekly cisplatin may be administered with...
...dissection is the preferred approach for patient...
...patients who have undergone ipsilat...
Oropharynx
...tients with lateralized oropharyngeal carcinoma...
...ateralized oropharyngeal cancer who have n...
...s with tumors extending to the midline tongue-ba...
...non-surgical approach should be offered...
...tients with biopsy-proven distant metastases sh...
...ET/CT scan at ≥12 weeks after completion...
...omplete radiation/chemoradiation and have...
...at ≥12 weeks shows mild FDG uptake in a node â‰...
...tment Algorithm for Management of the Neck in Pa...
...Treatment Algorithm for Management of the Neck...