Prevention And Management Of Chemotherapy-Induced Peripheral Neuropathy In Survivors Of Adult Cancers
Key Points
Key Points
- Chemotherapy-induced neuropathy (CIPN) is a serious clinical problem caused by a substantial number of cytotoxic drugs, including taxanes, platinums, vinca alkaloids, epothilones, eribulin, and bortezomib.
- No agents are recommended for the prevention of CIPN.
- Duloxetine is the only agent that has appropriate evidence to support its use, but the amount of benefit from duloxetine is limited.
- Therefore, prevention and minimizing risk are the primary objectives.
- Because patients with CIPN can have balance troubles and a higher chance of falling, it is reasonable to consider physical and/or occupational therapy approaches for patients with such CIPN-related disabilities.
Prevention
Prevent...
...vention of chemotherapy-induced peripheral neuro...
...ecommendation 1.1Clinicians should assess the...
...ation 1.2Clinicians should NOT offer,...
...endation 1.3Outside the context of a clinical tr...
...endation 1.4Clinicians should NOT offer t...
Treatment
...reatmen...
...chemotherapy-induced peripheral neuropathy...
...mmendation 2.1Clinicians should assess, and dis...
...reatment of chemotherapy-induced peripher...
...mendation 3.1For cancer patients e...
...tion 3.2Outside the context of a clinical trial, n...
Summary of Recommendations
...ary of RecommendationsHaving trouble...