Antiemetics

Publication Date: July 13, 2020

Key Points

Key Points

  • The development of increasingly effective antiemetic regimens over the last quarter century has greatly reduced the incidence of nausea and vomiting due to chemotherapy.
  • The recommended approach to preventing nausea and vomiting varies by the emetic risk of the treatment regimen.
  • Adherence to antiemetic guidelines has been linked with improved control of nausea and vomiting.
  • This update of the 2017 guideline adds guidance on the use of dexamethasone as a prophylactic antiemetic in patients receiving checkpoint inhibitors (CPIs).

Treatment

...atment...

...dult Patients

...lt patients, the addition of a checkpo...

...-Emetic-Risk Antineoplastic Ag...

...nts treated with cisplatin and othe...

...nts treated with an anthracycline com...

...metic-Risk Antineoplastic Agents...

...t patients treated with carboplatin area un...

...dult patients treated with moderate-emeti...

Adult patients treated with cyclophosphamide, doxo...

...-Emetic-Risk Antineoplastic...

...atients treated with low-emetic-risk antineo...

...tic Risk Antineoplastic Agents...

...patients treated with minimal emetic risk antine...

...eoplastic Combinations...

...dult patients treated with antineoplas...

...unctive Drugs

...razepam is a useful adjunct to antiemetic d...

...annabinoids

...ns insufficient for a recommendation r...

...plementary and Alternative Therapi...

...idence remains insufficient for a recommend...

...igh-Dose Chemotherapy With Stem-Cell or Bo...

...treated with high-dose chemotherapy...

...our-drug combination of an NK1 receptor antagonist...

...ntineoplastic Therapy...

...patients treated with multiday antineoplastic...

...ts treated with 4- or 5-day cisplatin...

...ugh Nausea and Vomiting...

...nts with breakthrough nausea or vomiting,...

...ho experience nausea or vomiting despite optimal...

...dronabinol and nabilone ( IC , I , M )6539

...se ( IC , L , M )6539...

...patory Nausea and Vomiti...

...patients should receive the most active...

...gh Emetic Risk Radiation Therapy...

...patients treated with high-emetic-risk radia...

...Emetic Risk Radiation Therapy...

Adult patients treated with moderate-emetic-ri...

...etic Risk Radiation Therapy

...treated with radiation therapy to the...

...nimal Emetic Risk Radiation Thera...

...ients treated with minimal emetic risk radiation t...

...adiation and Antineoplastic Agent Th...

...ents treated with concurrent radiation a...


...tric Patients...

...tic Risk Antineoplastic Agent...

...ric patients treated with high-emetic-risk antine...

...Pediatric patients treated with high-...

...Pediatric patients treated with high-...

...Emetic Risk Antineoplastic Agents...

...tric patients treated with moderate-emetic-risk...

...iatric patients treated with moderate-emetic-ris...

...tic Risk Antineoplastic Agents...

...ients treated with low-emetic-risk anti...

...nimal Emetic Risk Antineoplas...

...ric patients treated with minimal emetic...


...able 1. Emetic Risk of Single Intravenous...


...Risk of Single Oral Antineoplastic Agents...


Table 3. Antiemetic Dosing for Adults by Chemot...


...Emetic Risk in Adults by Site of Radiation The...


...e 5. Antiemetic Administration in Adul...