Antiemetics
Key Points
Key Points
- The development of increasingly effective antiemetic regimens over the last quarter century has greatly reduced the incidence of nausea and vomiting due to chemotherapy.
- The recommended approach to preventing nausea and vomiting varies by the emetic risk of the treatment regimen.
- Adherence to antiemetic guidelines has been linked with improved control of nausea and vomiting.
- This update of the 2017 guideline adds guidance on the use of dexamethasone as a prophylactic antiemetic in patients receiving checkpoint inhibitors (CPIs).
Treatment
...eatment...
...ult Patient...
...adult patients, the addition of a checkpoint in...
...metic-Risk Antineoplastic...
...treated with cisplatin and other high-emetic-r...
...ts treated with an anthracycline combined with...
...tic-Risk Antineoplastic Agent...
...atients treated with carboplatin are...
...reated with moderate-emetic-risk antineoplasti...
...lt patients treated with cyclophosphamide,...
...metic-Risk Antineoplastic Ag...
...ts treated with low-emetic-risk antineoplastic...
...c Risk Antineoplastic Agents...
...ult patients treated with minimal...
Antineoplastic Combina...
...ts treated with antineoplastic combination...
...nctive Drugs...
Lorazepam is a useful adjunct to antieme...
...nabinoid...
...ins insufficient for a recommendation regardi...
...ntary and Alternative Therapies
...ains insufficient for a recommendation f...
...ose Chemotherapy With Stem-Cell or Bone Marrow...
...tients treated with high-dose chemo...
...our-drug combination of an NK1 receptor antag...
...ltiday Antineoplastic Therapy
...treated with multiday antineoplastic a...
...ult patients treated with 4- or 5-day cisplatin r...
...hrough Nausea and Vomiting...
...h breakthrough nausea or vomiting, cl...
...atients who experience nausea or vomiting des...
...nd nabilone ( IC , I , M )6539...
...ise ( IC , L , M )65...
...ipatory Nausea and Vom...
...patients should receive the most active...
...ic Risk Radiation Thera...
...ult patients treated with high-emetic-risk radia...
...Emetic Risk Radiation Therapy...
...ts treated with moderate-emetic-risk rad...
...ow Emetic Risk Radiation T...
...s treated with radiation therapy to the brain...
...al Emetic Risk Radiation Therapy
...s treated with minimal emetic risk radiation thera...
...ncurrent Radiation and Antineoplas...
...patients treated with concurrent radiati...
...atric Patient...
...Emetic Risk Antineoplastic...
...ediatric patients treated with high-emetic-...
...pdated) Pediatric patients treated with high-emet...
...ed) Pediatric patients treated wit...
...etic Risk Antineoplastic Agent...
...ients treated with moderate-emetic-risk antineop...
...Pediatric patients treated with mod...
...etic Risk Antineoplastic Agent...
...ts treated with low-emetic-risk an...
...c Risk Antineoplastic Agents...
...atients treated with minimal emetic risk antin...
...etic Risk of Single Intravenous Antineoplastic A...
Table 2. Emetic Risk of Single Oral Antine...
...tiemetic Dosing for Adults by Chemotherapy...
...Emetic Risk in Adults by Site of Radiati...
...tic Administration in Adults by Radiation Therap...