Antiemetics
Key Points
Key Points
- The development of increasingly effective antiemetic regimens over the last quarter century has greatly reduced the incidence of nausea and vomiting due to chemotherapy.
- The recommended approach to preventing nausea and vomiting varies by the emetic risk of the treatment regimen.
- Adherence to antiemetic guidelines has been linked with improved control of nausea and vomiting.
- This update of the 2017 guideline adds guidance on the use of dexamethasone as a prophylactic antiemetic in patients receiving checkpoint inhibitors (CPIs).
Treatment
...Adult...
...r adult patients, the addition of a che...
...High-Emetic-Risk An...
...atients treated with cisplatin and other high-eme...
...t patients treated with an anthracycline comb...
...Moderate-Emet...
...tients treated with carboplatin area under th...
...reated with moderate-emetic-risk antineoplast...
...treated with cyclophosphamide, doxorubici...
...Low-Emetic-Risk A...
...dult patients treated with low-emetic-...
...Minimal Emetic Risk Antine...
...ents treated with minimal emetic risk antineopl...
...Antineop...
...t patients treated with antineoplastic combinatio...
...Adjunctive...
...useful adjunct to antiemetic drugs, but i...
...C...
...e remains insufficient for a recommendatio...
Complem...
...ins insufficient for a recommendation for or a...
...High-Dose Chemotherapy...
...ult patients treated with high-dose chem...
...ew) A four-drug combination of an NK1 receptor...
...Multiday Antine...
...reated with multiday antineoplastic agents shoul...
...ts treated with 4- or 5-day cisplatin regime...
...Breakthr...
...tients with breakthrough nausea or vomiting, clini...
...t patients who experience nausea or vomiti...
for dronabinol and nabilone ( IC , I , M...
...herwise ( IC , L ,...
...An...
...nts should receive the most active antie...
...High Emetic Ri...
...patients treated with high-emetic-r...
...Moderate Emetic R...
...s treated with moderate-emetic-risk radiation t...
...Low Emetic Risk...
...lt patients treated with radiation therapy to th...
...Minimal Emetic...
...treated with minimal emetic risk radiation th...
...Concurrent Radiatio...
...s treated with concurrent radiation and antineo...
...Pediatric Patients...
...High Emetic R...
...Pediatric patients treated with high-e...
(Updated) Pediatric patients treated...
...d) Pediatric patients treated with high-emetic-...
...Moderate Emetic Risk Antin...
...ediatric patients treated with moderate-...
...tric patients treated with moderate-...
...Low Emetic Risk Antineop...
...atients treated with low-emetic-risk a...
Minimal...
...iatric patients treated with minimal emet...
...ic Risk of Single Intravenous Antin...
...le 2. Emetic Risk of Single Oral Antineoplasti...
...etic Dosing for Adults by Chemotherapy...
...c Risk in Adults by Site of Radiation...
...le 5. Antiemetic Administration in Adults by R...