![American Society of Clinical Oncology American Society of Clinical Oncology](https://54d4f314-8f94-415c-acb7-fd0a6332f070.s3.amazonaws.com/403/403__asco-logo-lg__274272709.png?X-Amz-Content-Sha256=UNSIGNED-PAYLOAD&X-Amz-Algorithm=AWS4-HMAC-SHA256&X-Amz-Credential=AKIAU2BE4PNFKE2WZV7V%2F20240727%2Fus-east-1%2Fs3%2Faws4_request&X-Amz-Date=20240727T060734Z&X-Amz-SignedHeaders=host&X-Amz-Expires=86400&X-Amz-Signature=b698cc2fe05b631fb9935d6c2b372203218d93cc516cb906d3867e8ae00cd273)
Cervical Cancer Prevention
Key Points
Key Points
There are three prophylactic HPV vaccines approved and recommended in the United States, Europe, and many regions and countries: the bivalent (2vHPV; against HPV 16 and 18), quadrivalent (4vHPV; against HPV 6, 11, 16, and 18), and nine valent (9vHPV; against HPV 6, 11, 16, 18, 31, 33, 45, 52 and 58)
NOTE: Gardasil-9 (9-valent HPV vaccine) will be the only HPV vaccine available in the United States after May 2017.
Source: https://www.cdc.gov/vaccines/hcp/vis/vis-statements/hpv.html.
As a partial result of failures within different health care systems at both levels of prevention—vaccination, screening—and disease treatment/management, there are large regional and global disparities in cervical cancer incidence and mortality. Consequently ASCO has established a process for resource-stratified guidelines.
Prevention
Preventi...
...f Resource Stratification: Primary Preven...
In Maximal And Enhanced Resource Settings
...mal And Enhanced Resource Settings...
...lic health authorities, ministries of health, and...
...th authorities may set the upper end...
...ls 9–14 years of age who are immune c...
...ths ( EB , H , S )614...
...12–15 months (EB, L, W)614...
...≥15 years of age at the time of the first d...
...les who have received one dose and a...
...ion of cervical cancer, if there is l...
...of cervical cancer in maximal or enha...
In Limited Resource Settings
...d Resource Settings...
...th authorities, ministries of health, and primar...
...girls starting at 9 years of age w...
at least 6 months ( EB , H...
...12–15 months ( EB , L , M )614...
If there are sufficient resources remaining aft...
...ntion of cervical cancer in limited resou...
In Basic Settings
In Basic Settin...
...lth authorities, ministries of health, and pr...
...ting at 9 years of age who are immu...
...6 months ( EB , H , S )614...
...to 12–15 months. ( EB , L , M )614...
...of priority populations should be emphasized. Wh...
...tion of cervical cancer in basic res...
In All Resource Settings
...l Resource Settings
...who are HIV positive or immunosuppressed for oth...
...is NOT recommended for pregnant women. ( EB ,...
...ation strategy is recommended for women rece...