Cervical Cancer Prevention
Key Points
Key Points
- Vaccination is the optimal strategy for primary prevention of infection by some types of human papillomavirus that cause cervical cancer in the target population. There is no other preventive strategy for this cancer that can substitute for vaccination.
- There are three prophylactic HPV vaccines approved and recommended in the United States, Europe, and many regions and countries: the bivalent (2vHPV; against HPV 16 and 18), quadrivalent (4vHPV; against HPV 6, 11, 16, and 18), and nine valent (9vHPV; against HPV 6, 11, 16, 18, 31, 33, 45, 52 and 58)
- NOTE: Gardasil-9 (9-valent HPV vaccine) will be the only HPV vaccine available in the United States after May 2017. Source: https://www.cdc.gov/vaccines/hcp/vis/vis-statements/hpv.html.
- As a partial result of failures within different health care systems at both levels of prevention—vaccination, screening—and disease treatment/management, there are large regional and global disparities in cervical cancer incidence and mortality. Consequently ASCO has established a process for resource-stratified guidelines.
Prevention
...reventio...
...mework of Resource Stratification: Prima...
In Maximal And Enhanced Resource Settings
...n Maximal And Enhanced Resource Setting...
...authorities, ministries of health, a...
...ealth authorities may set the upper en...
...ls 9–14 years of age who are immun...
...nths ( EB , H , S )614
...12–15 months ( EB , L , W )614...
...ars of age at the time of the first dose/initiati...
...ales who have received one dose and are...
...w vaccine coverage of the priority f...
...accine coverage of girls is ≥50%, then va...
In Limited Resource Settings
...imited Resource Settings...
...h authorities, ministries of health, and primary...
...arting at 9 years of age who are immun...
...months ( EB , H , S )614...
...e up to 12–15 months ( EB , L , M )614...
...re are sufficient resources remaining after vacc...
...on of cervical cancer in limited resourc...
In Basic Settings
...Basic Settings...
...blic health authorities, ministries...
...starting at 9 years of age who are i...
...t 6 months ( EB , H , S...
...12–15 months. ( EB , L , M )614...
...verage of priority populations should be emp...
...evention of cervical cancer in basic r...
In All Resource Settings
...ll Resource Settings...
...o are HIV positive or immunosuppressed for...
...accination is NOT recommended for pre...
...trategy is recommended for women r...
...alifying Statements: If boys are vaccinated...