Cervical Cancer Prevention

Publication Date: March 17, 2017

Key Points

Key Points

Vaccination is the optimal strategy for primary prevention of infection by some types of human papillomavirus that cause cervical cancer in the target population. There is no other preventive strategy for this cancer that can substitute for vaccination.

There are three prophylactic HPV vaccines approved and recommended in the United States, Europe, and many regions and countries: the bivalent (2vHPV; against HPV 16 and 18), quadrivalent (4vHPV; against HPV 6, 11, 16, and 18), and nine valent (9vHPV; against HPV 6, 11, 16, 18, 31, 33, 45, 52 and 58)

NOTE: Gardasil-9 (9-valent HPV vaccine) will be the only HPV vaccine available in the United States after May 2017.
Source: https://www.cdc.gov/vaccines/hcp/vis/vis-statements/hpv.html.

As a partial result of failures within different health care systems at both levels of prevention—vaccination, screening—and disease treatment/management, there are large regional and global disparities in cervical cancer incidence and mortality. Consequently ASCO has established a process for resource-stratified guidelines.

Prevention

...vention...

...amework of Resource Stratification: Pr...


In Maximal And Enhanced Resource Settings

...al And Enhanced Resource Sett...

...blic health authorities, ministries of h...


...ublic health authorities may set the...


...14 years of age who are immune competent,...


...6 months ( EB , H , S )614...

...o 12–15 months (EB, L, W)6...


...ars of age at the time of the firs...


...males who have received one dose and...


...vention of cervical cancer, if there is low...


...f cervical cancer in maximal or enh...


In Limited Resource Settings

...ed Resource Settings...

...h authorities, ministries of health, and p...


...arting at 9 years of age who are immune compe...


...least 6 months ( EB , H , S )614

...12–15 months ( EB , L , M )61...


...sufficient resources remaining after vaccinatin...


...revention of cervical cancer in lim...


In Basic Settings

...Basic Settings

...th authorities, ministries of health, and pri...


...ls starting at 9 years of age who are im...


...6 months ( EB , H , S...

...2–15 months. ( EB , L , M )614...


...gh coverage of priority populations should be...


...evention of cervical cancer in basic resource set...


In All Resource Settings

...n All Resource S...

...re HIV positive or immunosuppressed for...


...is NOT recommended for pregnant women. ( EB...


...vaccination strategy is recommended for...