Cardiac Dysfunction - Prevention and Monitoring in Cancer Survivors
Key Points
Key Points
- Cardiac dysfunction is a serious side effect of certain cancer-directed therapies that can interfere with the efficacy of treatment, decrease quality of life, or impact the actual survival of the cancer patient.
- Heart failure (HF), presenting during or after completion of cancer treatment, is a well-recognized complication that begins with risk factors known to be associated with the development of HF, including the toxicity of chemotherapy and/or radiation (stage A), and is commonly progressive after structural changes to the heart occur.
- The initial manifestation may be asymptomatic.
- Onset may also be responsible for interruption or discontinuation of cancer-directed therapy, potentially reducing the chance for long-term survival.
Risk
Risk
...ed that cancer patients who meet any of th...
...recommendation can be made on the risk of ca...
Prevention
Prevention
...n PRIOR TO Initiation of Therapy...
...minimize the use of potentially cardiotoxic t...
...ians should perform a comprehensive assessment i...
...ention DURING Potentially Cardiotoxic Cance...
...hould screen for and actively mana...
...ay incorporate a number of strategies, inclu...
...patients who require mediastinal RT wh...
Surveillance
...urveilla...
Monitoring During Treatme...
...icians should complete a careful history and phys...
...mendation 4.2...
...iogram for diagnostic work-up ( EB ,...
...ardiac magnetic resonance imaging (MRI) or multi-...
...diac biomarkers (troponins, natriuretic...
...ral to a cardiologist based on findings....
...surveillance imaging may be offered during...
...onitoring After Treatmen...
...cians should complete a careful history and physic...
Recommendation 5.1.1
...ocardiogram for diagnostic work-up ( EB...
...ardiac MRI or MUGA if echocardiogram is...
...cardiac biomarkers (troponins, natriu...
...cardiologist based on findings (IC, B, S...
...chocardiogram may be performed 6–12 months af...
...rdiac MRI or MUGA may be offered for s...
...dentified to have asymptomatic cardiac dysfunc...
...o recommendations can be made regard...
...should regularly evaluate and manage cardi...