Anaphylaxis

Publication Date: December 17, 2023
Last Updated: October 28, 2024

Diagnosis

Recommendation 1 (CBS)

We recommend obtaining a baseline serum tryptase (bST) in patients presenting with a history of recurrent, idiopathic, or severe anaphylaxis, particularly those presenting with hypotension.

(S, M )
620

Infants and Toddlers

Anaphylaxis in Infants and Toddlers

Recommendation 8 (CBS)

We suggest that clinicians use current NIAID/FAAN or WAO anaphylaxis criteria to assist in the diagnosis of anaphylaxis in infants/toddlers, because there are no criteria specific to this age group.

(C, L )
620

Recommendation 9 (CBS)

We suggest clinicians be aware that, in infants and toddlers, patient age does not correlate with reaction severity.

(C, VL )
620

Recommendation 10 (CBS)

We suggest clinicians be aware that anaphylaxis is unlikely to be the initial reaction to a food or medication on first exposure in infants. (C, L )
620

Recommendation 11 (CBS)

We suggest clinicians be aware that parents of infants and toddlers may report age-specific symptoms that are less often reported by older children and adults.

(C, VL )
620

Recommendation 12 (CBS)

We suggest clinicians prescribe either the 0.1 mg or the 0.15 mg EAI dose for infants/toddlers weighing less than 15 kg.

(C, L )
620

Overview

Title

Anaphylaxis

Authoring Organizations

American College of Allergy, Asthma, and Immunology

American Academy of Allergy, Asthma & Immunology