Acute Pancreatitis

Publication Date: March 1, 2018

Key Points

Key Points

  • Acute pancreatitis (AP) is an inflammatory condition of the pancreas that can cause local injury, systemic inflammatory response syndrome (SIRS) and organ failure.
  • The incidence of AP ranges from 5–30 cases per 100,000, and there is evidence that the incidence is rising in recent years.
  • The overall case fatality rate for AP is roughly 5% and is expectedly higher for more severe disease.
  • The most common causes of AP remain gallstones and alcohol, which together comprise 80% of cases. The remainder of cases is due to less common causes, including drug reactions, pancreatic solid and cystic malignancies, and hypertriglyceridemia.
  • Patients with AP frequently suffer from abdominal pain, nausea, and vomiting.
  • The diagnosis of AP requires ≥2 of the following features:
    • Characteristic abdominal pain
    • Biochemical evidence of pancreatitis (i.e. amylase or lipase elevated >3 times the upper limit of normal) and/or
    • Radiographic evidence of pancreatitis on cross-sectional imaging

Treatment

...atment

...ecommendations of the AGA Clinical Guideline for t...

...s with acute pancreatitis, AGA suggest...

...atients with acute pancreatitis, AGA...

...ients with predicted severe acute panc...

...with acute biliary pancreatitis and...

...nts with acute pancreatitis, AGA r...

...with acute pancreatitis and inability to feed ora...

...nts with predicted severe or necrotizing pancr...

In patients with acute biliary pancreatitis, AG...

...atients with acute alcoholic pancreati...