Laboratory Evaluation of Functional Diarrhea and Diarrhea-Predominant Irritable Bowel Syndrome in Adults
Treatment
Table 1. Summary of Recommendations of AGA Clinical Guideline on the Laboratory Evaluation of Functional Diarrhea and Diarrhea-Predominant Irritable Bowel Syndrome in Adults (IBS-D)
1. In patients presenting with chronic diarrhea, AGA suggests the use of stool tests, either fecal calprotectin or fecal lactoferrin to screen for inflammatory bowel disease. ( Low , Conditional (weak) )
612
2. In patients presenting with chronic diarrhea, AGA suggests against the use of blood tests erythrocyte sedimentation rate (ESR) or C-reactive protein (CRP) to screen for inflammatory bowel disease. ( Low , Conditional (weak) )
612
3. In patients presenting with chronic diarrhea, AGA recommends stool testing for Giardia. ( High , Strong )
612
4. In patients presenting with chronic diarrhea with no travel history to or recent immigration from high risk areas, AGA suggests against testing stools for ova and parasites (other than Giardia). ( Low , Conditional (weak) )
612
5. In patients presenting with chronic diarrhea, AGA recommends testing for celiac disease with IgA tTG and a second test to detect celiac disease in the setting of IgA deficiency. ( Moderate , Strong )
612
6. In patients presenting with chronic diarrhea, AGA suggests testing for bile acid diarrhea. ( Low , Conditional (weak) )
612
7. In patients presenting with chronic diarrhea, AGA makes no recommendation for the use of currently available serologic tests for diagnosis of IBS. ( Evidence Gap , No recommendation )
612
Recommendation Grading
Overview
Title
Laboratory Evaluation of Functional Diarrhea and Diarrhea-Predominant Irritable Bowel Syndrome in Adults
Authoring Organization
American Gastroenterological Association
Publication Month/Year
September 2, 2019
Supplemental Implementation Tools
Quick-Reference Guide, Quick-Reference Guide, Patient Information
Document Type
Guideline
External Publication Status
Published
Country of Publication
US
Inclusion Criteria
Female, Male, Adult, Older adult
Health Care Settings
Ambulatory, Laboratory services
Intended Users
Nurse, nurse practitioner, physician, physician assistant
Scope
Assessment and screening, Diagnosis
Diseases/Conditions (MeSH)
D003967 - Diarrhea
Keywords
functional diarrhea, irritable bowel syndrome (IBS), IBS-D
Supplemental Methodology Resources
Methodology
Number of Source Documents
112
Literature Search Start Date
March 30, 2017
Literature Search End Date
September 1, 2018