Antimicrobial Prophylaxis in Surgery

Authoring Organizations

Publication Month/Year

May 1, 2012

Last Updated Month/Year

September 12, 2023

Document Type


External Publication Status


Country of Publication


Document Objectives

The guidelines are intended to provide practitioners with a standardized approach to the rational, safe, and effective use of antimicrobial agents for the prevention of surgical-site infections (SSIs) based on currently available clinical evidence and emerging issues.

Target Patient Population

Patients undergo invasive procedure

Inclusion Criteria

Male, Female, Adolescent, Adult, Child, Older adult

Health Care Settings

Hospital, Outpatient, Operating and recovery room

Intended Users

Epidemiology infection prevention, nurse, nurse practitioner, physician, physician assistant


Assessment and screening, Prevention

Diseases/Conditions (MeSH)

D013502 - General Surgery, D019072 - Antibiotic Prophylaxis, D003107 - Colorectal Surgery, D013903 - Thoracic Surgery


prophylaxis, surgery, antimicrobial prophylaxis

Source Citation

Bratzler DW, Dellinger EP, Olsen KM, et al. Clinical practice guidelines for antimicrobial prophylaxis in surgery. Am J Health-Syst Pharm. 2013; 70:195–283.