Role Of Postoperative Radiation Therapy For Endometrial Cancer

Publication Date: June 1, 2017
Last Updated: March 14, 2022

Guideline statements

Which patients with endometrioid endometrial cancer require no additional therapy after hysterectomy?

Following total abdominal hysterectomy with or without node dissection, no radiation therapy is a reasonable option for patients with:
  • 1) no residual disease in the hysterectomy specimen despite positive biopsy OR
(Strong, Low)
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  • 2) grade 1 or 2 cancers with either no invasion or less than 50% myometrial invasion, especially when no other high-risk features are present.
(, )
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Patients with the following pathologic features may be reasonably treated with or without vaginal brachytherapy:
  • 1) grade 3 cancers without myometrial invasion OR
(Strong, Low)
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  • 2) grade 1 or 2 cancers with less than 50% myometrial invasion and higher risk features such as age greater than 60 and/or lymphovascular space invasion.
(, )
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Overview

Title

Role Of Postoperative Radiation Therapy For Endometrial Cancer

Authoring Organization

American Society for Radiation Oncology