Evidence-Based Management Of Anticoagulant Therapy
Publication Date: February 1, 2012
Last Updated: March 14, 2022
Recommendations
VKA—Initiation of Therapy
Initial Dose Selection—Loading Dose
For patients sufficiently healthy to be treated as outpatients, we suggest initiating VKA therapy with warfarin 10 mg daily for the fi rst 2 days followed by dosing based on INR measurements rather than starting with the estimated maintenance dose. (2, C)
307795
Title
Evidence-Based Management Of Anticoagulant Therapy
Authoring Organization
American College of Chest Physicians