Role of Endoscopy in the Assessment and Treatment of Esophageal Cancer

Publication Date: March 1, 2013
Last Updated: March 14, 2022


We recommend EUS and FNA (when indicated), in conjunction with cross-sectional imaging, for the accurate staging of esophageal carcinoma. (M)

We suggest that EMR or ESD be used for the treatment and staging of nodular BE and suspected intramucosal SCC and adenocarcinoma. (L)

We suggest that APC, heater probe, cryotherapy, or radiofrequency ablation not be used as monotherapy with curative intent for mucosal esophageal cancer. (L)

We suggest that ablative techniques such as APC, heater probe, cryotherapy, or radiofrequency ablation may have a role in ablation of remaining high-risk tissue following resection. (L)

We recommend that esophageal stent placement is the preferred method for palliation of dysphagia and fistulae secondary to esophageal cancer because it provides immediate and durable relief in the majority of patients. (M)

We suggest that a variety of factors, including patient preferences, quality of life, and prognosis be addressed with the patient and family before initiating endoscopic palliation for esophageal malignancy. (L)

Recommendation Grading




Role of Endoscopy in the Assessment and Treatment of Esophageal Cancer

Authoring Organization

Publication Month/Year

March 1, 2013

Last Updated Month/Year

August 22, 2023

Document Type


External Publication Status


Country of Publication


Inclusion Criteria

Female, Male, Adolescent, Adult, Child, Older adult

Health Care Settings

Ambulatory, Emergency care, Hospital, Outpatient

Intended Users

Nurse, nurse practitioner, physician, physician assistant


Assessment and screening, Treatment

Diseases/Conditions (MeSH)

D000230 - Adenocarcinoma, D002294 - Carcinoma, Squamous Cell, D001471 - Barrett Esophagus


Barrett's esophagus, Esophageal cancer, adenocarcinoma

Source Citation

Evans, J. A., Early, D. S., Chandraskhara, V., Chathadi, K. V., Fanelli, R. D., Fisher, D. A., … Cash, B. D. (2013). The role of endoscopy in the assessment and treatment of esophageal cancer. Gastrointestinal Endoscopy, 77(3), 328–334. doi:10.1016/j.gie.2012.10.001