Consistent engagement with current medical literature enables clinicians to apply the latest evidence-based treatment and integrate research into clinical practice. This approach enhances patient outcomes by facilitating more effective and individualized care, especially for gastrointestinal health disorders.

Today, we’re showcasing some of the latest gastroenterology-related articles published recently across medical journals. The topics in today’s rundown include GERD, IBS, and more.

GERD Articles

First Report of Successful Endoscopic Full-Thickness Plication Using the GERDx System to Treat Refractory GERD After Sleeve Gastrectomy

  • ACG Case Reports Journal, February 2026
  • Description: Gastroesophageal reflux disease frequently develops or worsens after sleeve gastrectomy (SG), and symptoms may persist despite optimal proton pump inhibitor therapy due to postsurgical anatomical changes. Endoscopic full-thickness plication is a minimally invasive approach used to reinforce the gastroesophageal junction barrier. However, its feasibility after SG remains unclear given restricted retroflexion and reduced gastric compliance.
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Association of GERD with Sleeve Gastrectomy: An Unintended Consequence

  • Current Diabetes Reports, January 2026
  • Description: The purpose of this review is to summarize the prevalence of and predictors of GERD after laparoscopic sleeve gastrectomy, physiological mechanisms that explain the risk, and novel surgical management and strategy.
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The Lyon Score, a Novel GERD Scoring System, Significantly Predicts Response to PPIs in GERD Patients With Chronic Cough

  • Neurogastroenterology and Motility, December 2025
  • Description: Chronic cough is a frequent and troublesome extraesophageal manifestation of GERD, with poor response rates to proton pump inhibitors and limited diagnostic tools to predict treatment efficacy. The Lyon score, a novel composite metric integrating reflux parameters, has shown promise in typical GERD but remains untested in chronic cough.
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IBS Articles

A Pilot, Randomized, Placebo-Controlled Trial of Rimegepant on Visceral Sensation and Symptoms in Nonconstipation IBS Pain

  • The American Journal of Physiology-Gastroenterology and Liver Physiology, March 2026
  • Description: Visceral hypersensitivity is a pivotal mechanism in pain associated with irritable bowel syndrome (IBS). Calcitonin gene-related peptide (CGRP) is expressed by visceral afferents. The aim of this study was to evaluate the efficacy of rimegepant, a CGRP antagonist, on abdominal pain, rectal compliance and sensation, gut transit, and safety in participants with nonconstipation IBS with pain.
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Development and Implementation of Novel Virtual Triage and Exploration of Attitudes Towards the Potential Use of Artificial Intelligence in the Irritable Bowel Syndrome (IBS) Dietetic Pathway

  • Journal of Human Nutrition and Dietetics, February 2026
  • Description: The aim of this work was to develop and implement a novel semi-automation virtual triage, assess its impact in the IBS pathway and to investigate attitudes towards the use of artificial intelligence in triage and dietetic healthcare.
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Efficacy of Hypnotherapy in the Treatment of Irritable Bowel Syndrome (IBS): A Systematic Review and Meta-Analysis

  • The American Journal of Clinical Hypnosis, March 2026
  • Description: Irritable bowel syndrome (IBS) is a functional gastrointestinal disorder that is characterized by abdominal pain and altered bowel habits and has a significant impact on quality of life. The current study aimed to assess the efficacy of hypnotherapy as a management strategy of IBS.
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Ulcerative Colitis Articles

Intestinal Ultrasound Scan in Acute Severe Ulcerative Colitis in Children: A Multicenter Prospective Study on Behalf of the Porto IBD Working Group of ESPGHAN

  • Gastroenterology, March 2026
  • Description: The aim of this study was to evaluate the potential role of intestinal ultrasound scan (IUS) in predicting short-term treatment outcomes in pediatric acute severe ulcerative colitis (ASUC).
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Ulcerative Colitis, Frailty, and Beyond

  • Expert Review of Gastroenterology & Hepatology, March 2026
  • Description: Frailty is a geriatric construct that is increasingly pertinent to patients with ulcerative colitis (UC). Understanding how frailty and UC interact will be imperative to incorporating frailty into clinical decision-making in UC.
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Sleep Impairment in Patients with Ulcerative Colitis: A Cross-Sectional Assessment of Clinical, Inflammatory, Metabolic and Behavioral Factors

  • BMC Gastroenterology, March 2026
  • Description: Sleep impairment is common in ulcerative colitis (UC) and may persist during clinical remission. This study evaluated the clinical, inflammatory, metabolic, and behavioral features to better characterize the factors associated with poor sleep in patients with UC.
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Look forward to more journal-focused topics in the coming weeks. 

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